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Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma

Immunohistochemical and medical characterization of the basal-like subtype of invasive breast carcinoma.

 

OBJECTIVE
Expression profiling research categorized breast carcinomas into estrogen receptor (ER)+/luminal, regular breast-like, HER2 overexpressing, and basal-like teams, with the latter two related to poor outcomes.
At the moment, there exist medical assays that determine ER+/luminal and HER2-overexpressing tumors, and we sought to develop a medical assay for breast basal-like tumors.
METHODS

To determine an immunohistochemical profile for breast basal-like tumors, we collected a collection of identified basal-like tumors and examined them for protein patterns which are attribute of this subtype. Subsequent, we examined the importance of those protein patterns utilizing tissue microarrays and evaluated the prognostic significance these findings.

RESULTS
Utilizing a panel of 21 basal-like tumors, which was decided utilizing gene expression profiles, we noticed that this subtype was sometimes immunohistochemically adverse for estrogen receptor and HER2 however constructive for basal cytokeratins, HER1, and/or c-KIT.
Utilizing breast carcinoma tissue microarrays representing 930 sufferers with 17.4-year imply follow-up, basal cytokeratin expression was related to low disease-specific survival.
HER1 expression was noticed in 54% of circumstances constructive for basal cytokeratins (versus 11% of adverse circumstances) and was related to poor survival impartial of nodal standing and measurement.
c-KIT expression was extra widespread in basal-like tumors than in different breast cancers however didn’t affect prognosis.
CONCLUSIONS
A panel of 4 antibodies (ER, HER1, HER2, and cytokeratin 5/6) can precisely determine basal-like tumors utilizing normal obtainable medical instruments and exhibits excessive specificity. These research present that many basal-like tumors categorical HER1, which suggests candidate medication for analysis in these sufferers.
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Caspase 3 Assay Kit

20-abx294003
  • EUR 1506.00
  • EUR 548.40
  • EUR 924.00
  • 100 tests
  • 20 tests
  • 50 tests

Poly-Caspase Assay Kit

20-abx299016
  • EUR 1562.40
  • EUR 698.40
  • 100 tests
  • 25 tests

Caspase 6 Assay Kit

20-abx299018
  • EUR 1562.40
  • EUR 698.40
  • 100 tests
  • 25 tests

Caspase 1 Assay Kit

20-abx299019
  • EUR 1638.00
  • EUR 754.80
  • 100 tests
  • 25 tests

Caspase 8 Assay Kit

20-abx299020
  • EUR 1562.40
  • EUR 698.40
  • 100 tests
  • 25 tests

Caspase 9 Assay Kit

20-abx299021
  • EUR 1562.40
  • EUR 698.40
  • 100 tests
  • 25 tests

Poly-Caspase Assay Kit

abx299022-2550tests 25-50 tests
EUR 830.4

Caspase 1 Assay Kit

abx299023-2550tests 25-50 tests
EUR 830.4

Poly-Caspase Assay Kit

20-abx299025
  • EUR 1562.40
  • EUR 698.40
  • 100 tests
  • 25 tests

Caspase 2 Assay Kit

abx299026-25tests 25 tests
EUR 698.4

Caspase 10 Assay Kit

abx299027-100tests 100 tests
EUR 1562.4

Caspase 9 Assay Kit

20-abx299035
  • EUR 1562.40
  • EUR 698.40
  • 100 tests
  • 25 tests

Glycerol Cell-Based Assay Kit

K977-100
EUR 588

99999 CAP 13-415

99999-13 1000/pk
EUR 262.8
Description: Disposable Screw Cap Culture Tubes; DSCCT's, Caps

Caspase 3 Fluorometric Assay Kit

55R-1269 25 assays
EUR 332.4
Description: Assay Kit for detection of Capase 3 activity in the research laboratory

Caspase 3 Colorimetric Assay Kit

55R-1270 25 assays
EUR 332.4
Description: Assay Kit for detection of Capase 3 activity in the research laboratory

Caspase 1 Fluorometric Assay Kit

55R-1272 25 assays
EUR 332.4
Description: Assay Kit for detection of Capase 1 activity in the research laboratory

Caspase 1 Colorimetric Assay Kit

55R-1273 25 assays
EUR 332.4
Description: Assay Kit for detection of Capase 1 activity in the research laboratory

Caspase 8 Fluorometric Assay Kit

55R-1274 25 assays
EUR 332.4
Description: Assay Kit for detection of Capase 8 activity in the research laboratory

Caspase 8 Colorimetric Assay Kit

55R-1275 25 assays
EUR 332.4
Description: Assay Kit for detection of Capase 8 activity in the research laboratory

Caspase 6 Fluorometric Assay Kit

55R-1276 25 assays
EUR 344.4
Description: Assay Kit for detection of Capase 6 activity in the research laboratory

Caspase 6 Colorimetric Assay Kit

55R-1277 25 assays
EUR 340.8
Description: Assay Kit for detection of Capase 6 activity in the research laboratory

Caspase 2 Fluorometric Assay Kit

55R-1278 25 assays
EUR 340.8
Description: Assay Kit for detection of Capase 2 activity in the research laboratory

Caspase 2 Colorimetric Assay Kit

55R-1279 25 assays
EUR 363.6
Description: Assay Kit for detection of Capase 2 activity in the research laboratory

Caspase 9 Fluorometric Assay Kit

55R-1280 25 assays
EUR 332.4
Description: Assay Kit for detection of Capase 9 activity in the research laboratory

Caspase 9 Colorimetric Assay Kit

55R-1281 25 assays
EUR 355.2
Description: Assay Kit for detection of Capase 9 activity in the research laboratory

Caspase 5 Fluorometric Assay Kit

55R-1282 25 assays
EUR 340.8
Description: Assay Kit for detection of Capase 5 activity in the research laboratory

Caspase 5 Colorimetric Assay Kit

55R-1283 25 assays
EUR 363.6
Description: Assay Kit for detection of Capase 5 activity in the research laboratory

Caspase 10 Fluorometric Assay Kit

55R-1284 25 assays
EUR 340.8
Description: Assay Kit for detection of Capase 10 activity in the research laboratory

Caspase 10 Colorimetric Assay Kit

55R-1285 25 assays
EUR 363.6
Description: Assay Kit for detection of Capase 10 activity in the research laboratory

Caspase 4 Fluorometric Assay Kit

55R-1286 25 assays
EUR 363.6
Description: Assay Kit for detection of Capase 4 activity in the research laboratory

Caspase 4 Colorimetric Assay Kit

55R-1287 25 assays
EUR 374.4
Description: Assay Kit for detection of Capase 4 activity in the research laboratory

Caspase 3/7 Assay Kit

20-abx299017
  • EUR 1562.40
  • EUR 698.40
  • 100 tests
  • 25 tests

Caspase 3/7 Assay Kit

abx299024-2550tests 25-50 tests
EUR 830.4

Caspase 3/7 Assay Kit

20-abx299028
  • EUR 1431.60
  • EUR 698.40
  • 100 tests
  • 25 tests

Caspase-1 Activity Assay Kit

AR4003-100Assays 100 Assays
EUR 616.8

Caspase-1 Activity Assay Kit

AR4003-25Assays 25 Assays
EUR 283.2

Caspase-1 Activity Assay Kit

AR4003-50Assays 50 Assays
EUR 408

Caspase-2 Activity Assay Kit

AR4004-100Assays 100 Assays
EUR 616.8

Caspase-2 Activity Assay Kit

AR4004-25Assays 25 Assays
EUR 283.2

Caspase-2 Activity Assay Kit

AR4004-50Assays 50 Assays
EUR 408

QuantiFluo Caspase-3 Assay Kit

DCS3-100 100
EUR 330
Description: Quantitative determination of the apoptosis target caspase-3 activity by fluorimetry (400/490nm) method. Procedure: 60 min. Kit size: 100 tests. Shelf life: 12 months.

Caspase-5 Fluorometric Assay Kit

K2195-100 100 assays
EUR 602.4

Caspase-5 Fluorometric Assay Kit

K2195-200 200 assays
EUR 835.2

Caspase-5 Fluorometric Assay Kit

K2195-25 25 assays
EUR 285.6

Caspase-5 Fluorometric Assay Kit

K2195-400 400 assays
EUR 1336.8

Caspase-5 Colorimetric Assay Kit

K2196-100 100 assays
EUR 634.8

Caspase-5 Colorimetric Assay Kit

K2196-200 200 assays
EUR 870

Caspase-5 Colorimetric Assay Kit

K2196-25 25 assays
EUR 301.2

Caspase-5 Colorimetric Assay Kit

K2196-400 400 assays
EUR 1387.2

Caspase-10 Colorimetric Assay Kit

K2197-100 100 assays
EUR 634.8

Caspase-10 Colorimetric Assay Kit

K2197-200 200 assays
EUR 885.6

Caspase-10 Colorimetric Assay Kit

K2197-25 25 assays
EUR 301.2

Caspase-10 Colorimetric Assay Kit

K2197-400 400 assays
EUR 1336.8

Caspase-4 Fluorometric Assay Kit

K2198-100 100 assays
EUR 634.8

Caspase-4 Fluorometric Assay Kit

K2198-200 200 assays
EUR 885.6

Caspase-4 Fluorometric Assay Kit

K2198-25 25 assays
EUR 301.2

Caspase-4 Fluorometric Assay Kit

K2198-400 400 assays
EUR 1336.8

Caspase-4 Colorimetric Assay Kit

K2199-100 100 assays
EUR 668.4

Caspase-4 Colorimetric Assay Kit

K2199-200 200 assays
EUR 885.6

Caspase-4 Colorimetric Assay Kit

K2199-25 25 assays
EUR 319.2

Caspase-4 Colorimetric Assay Kit

K2199-400 400 assays
EUR 1336.8

Caspase 1 Assay Kit, green

KF17201 25 Tests
EUR 390

Caspase 2 Assay Kit, green

KF17202 25 Tests
EUR 364.8

Caspase 6 Assay Kit, green

KF17204 25 Tests
EUR 364.8

Caspase 8 Assay Kit, green

KF17205 25 Tests
EUR 364.8

Caspase 9 Assay Kit, green

KF17206 25 Tests
EUR 364.8

Caspase 10 Assay Kit, green

KF17207 25 Tests
EUR 364.8

Caspase 9 Assay Kit, red

KF17302 25 Tests
EUR 364.8

660 Caspase-1 Assay Kit

KF17362 25-50 Tests
EUR 418.8

Caspase-12 Fluorometric Assay Kit

K139-100
EUR 601.2

Caspase-12 Fluorometric Assay Kit

K139-25
EUR 307.2

Caspase-4 Fluorometric Assay Kit

K126-100
EUR 561.6

Caspase-4 Fluorometric Assay Kit

K126-200
EUR 738

Caspase-4 Fluorometric Assay Kit

K126-25
EUR 255.6

Caspase-4 Fluorometric Assay Kit

K126-400
EUR 1110

Caspase-4 Colorimetric Assay Kit

K127-100
EUR 561.6

Caspase-4 Colorimetric Assay Kit

K127-200
EUR 738

Caspase-4 Colorimetric Assay Kit

K127-25
EUR 274.8

Caspase-4 Colorimetric Assay Kit

K127-400
EUR 1149.6

Caspase-5 Fluorometric Assay Kit

K122-100
EUR 523.2

Caspase-5 Fluorometric Assay Kit

K122-200
EUR 698.4

Caspase-5 Fluorometric Assay Kit

K122-25
EUR 242.4

Caspase-5 Fluorometric Assay Kit

K122-400
EUR 1149.6

Caspase-5 Colorimetric Assay Kit

K123-100
EUR 561.6

Caspase-5 Colorimetric Assay Kit

K123-200
EUR 738

Caspase-5 Colorimetric Assay Kit

K123-25
EUR 255.6

Caspase-5 Colorimetric Assay Kit

K123-400
EUR 1149.6

Identification and characterization of ovarian cancer-initiating cells from major human tumors.

The goal of this examine was to determine and characterize a self-renewing subpopulation of human ovarian tumor cells (ovarian cancer-initiating cells, OCICs) absolutely succesful of serial propagation of their authentic tumor phenotype in animals.
Ovarian serous adenocarcinomas had been disaggregated and subjected to development circumstances selective for self-renewing, nonadherent spheroids beforehand proven to derive from tissue stem cells. To affirm the existence of OCICs, xenoengraftment of as few as 100 dissociated spheroid cells allowed full recapitulation of the unique tumor (grade 2/grade three serous adenocarcinoma), whereas >10(5) unselected cells remained nontumorigenic.
Stemness properties of OCICs (below stem cell-selective circumstances) had been additional established by cell proliferation assays and reverse transcription-PCR, demonstrating enhanced chemoresistance to the ovarian most cancers chemotherapeutics cisplatin or paclitaxel and up-regulation of stem cell markers (Bmi-1, stem cell issue, Notch-1, Nanog, nestin, ABCG2, and Oct-4) in contrast with parental tumor cells or OCICs below differentiating circumstances. To determine an OCIC cell floor phenotype, spheroid immunostaining confirmed important up-regulation of the hyaluronate receptor CD44 and stem cell issue receptor CD117 (c-package), a tyrosine kinase oncoprotein.
Just like sphere-forming OCICs, injection of solely 100 CD44(+)CD117(+) cells might additionally serially propagate their authentic tumors, whereas 10(5) CD44(-)CD117(-) cells remained nontumorigenic. Primarily based on these findings, we assert that epithelial ovarian cancers derive from a subpopulation of CD44(+)CD117(+) cells, thus representing a potential therapeutic goal for this devastating illness.

Redefining endothelial progenitor cells through clonal evaluation and hematopoietic stem/progenitor cell principals.

The restricted vessel-forming capability of infused endothelial progenitor cells (EPCs) into sufferers with cardiovascular dysfunction could also be associated to a misunderstanding of the biologic potential of the cells. EPCs are typically recognized by cell floor antigen expression or counting in a commercially obtainable package that identifies “endothelial cell colony-forming models” (CFU-ECs).
Nonetheless, the origin, proliferative potential, and differentiation capability of CFU-ECs is controversial. In distinction, different EPCs with blood vessel-forming capability, termed endothelial colony-forming cells (ECFCs), have been remoted from human peripheral blood. We in contrast the perform of CFU-ECs and ECFCs and decided that CFU-ECs are derived from the hematopoietic system utilizing progenitor assays, and evaluation of donor cells from polycythemia vera sufferers harboring a Janus kinase 2 V617F mutation in hematopoietic stem cell clones.
Additional, CFU-ECs possess myeloid progenitor cell exercise, differentiate into phagocytic macrophages, and fail to kind perfused vessels in vivo. In distinction, ECFCs are clonally distinct from CFU-ECs, show sturdy proliferative potential, and kind perfused vessels in vivo.
Thus, these research set up that CFU-ECs will not be EPCs and the function of those cells in angiogenesis should be re-examined previous to additional medical trials, whereas ECFCs could function a potential remedy for vascular regeneration.

Human Versican (VS) ELISA Kit

DLR-VS-Hu-48T 48T
EUR 597.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Versican (VS) in samples from serum, plasma, tissue homogenates or other biological fluids.

Human Versican (VS) ELISA Kit

DLR-VS-Hu-96T 96T
EUR 776.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Versican (VS) in samples from serum, plasma, tissue homogenates or other biological fluids.

Mouse Versican (VS) ELISA Kit

DLR-VS-Mu-48T 48T
EUR 609.6
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Versican (VS) in samples from serum, plasma, tissue homogenates or other biological fluids.

Mouse Versican (VS) ELISA Kit

DLR-VS-Mu-96T 96T
EUR 793.2
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Versican (VS) in samples from serum, plasma, tissue homogenates or other biological fluids.

Human Versican (VS) ELISA Kit

RD-VS-Hu-48Tests 48 Tests
EUR 600

Human Versican (VS) ELISA Kit

RD-VS-Hu-96Tests 96 Tests
EUR 830.4

Mouse Versican (VS) ELISA Kit

RD-VS-Mu-48Tests 48 Tests
EUR 613.2

Mouse Versican (VS) ELISA Kit

RD-VS-Mu-96Tests 96 Tests
EUR 850.8

Human Versican (VS) ELISA Kit

RDR-VS-Hu-48Tests 48 Tests
EUR 626.4

Human Versican (VS) ELISA Kit

RDR-VS-Hu-96Tests 96 Tests
EUR 868.8

Mouse Versican (VS) ELISA Kit

RDR-VS-Mu-48Tests 48 Tests
EUR 640.8

Mouse Versican (VS) ELISA Kit

RDR-VS-Mu-96Tests 96 Tests
EUR 890.4

Cytochrome C Apoptosis Assay Kit

55R-1348 100 assays
EUR 1267.2
Description: Cytochrome C Apoptosis Kit for detection of apoptosis in the research laboratory

Cytochrome c Apoptosis Assay Kit

K2104-100 100 assays
EUR 835.2

CF488A and PI Apoptosis Assay Kit

30061 1KIT
EUR 339.6
Description: Minimum order quantity: 1 unit of 1KIT

CF488A TUNEL Assay Apoptosis Detection Kit

30063 1KIT
EUR 655.2
Description: Minimum order quantity: 1 unit of 1KIT

CF594 TUNEL Assay Apoptosis Detection Kit

30064 1KIT
EUR 655.2
Description: Minimum order quantity: 1 unit of 1KIT

CF640R TUNEL Assay Apoptosis Detection Kit

30074 1KIT
EUR 655.2
Description: Minimum order quantity: 1 unit of 1KIT

Cytochrome c Releasing Apoptosis Assay Kit

K257-100
EUR 810

Apoptosis & Necrosis Quantification Kit (50 assays)

30017 1KIT
EUR 297.6
Description: Minimum order quantity: 1 unit of 1KIT

CF488A and 7-AAD Apoptosis Assay Kit

30060 1KIT
EUR 339.6
Description: Minimum order quantity: 1 unit of 1KIT

VS-5584

9603-1
EUR 170.4

VS-5584

9603-5
EUR 496.8

VS-5584

HY-16585 5mg
EUR 207.6

Apoptosis and Necrosis Quantitation Kit Plus (50 assays)

30065 1KIT
EUR 290.4
Description: Minimum order quantity: 1 unit of 1KIT

Cell Meter™ TUNEL Apoptosis Assay Kit *Red Fluorescence*

22844 50 Tests
EUR 367.2

Cell Meter™ TUNEL Apoptosis Assay Kit *Green Fluorescence*

22849 50 Tests
EUR 367.2

EZClick? TUNEL ? in situ DNA Fragmentation/Apoptosis Assay Kit

K191-100
EUR 639.6

Human Versican (VS)CLIA Kit

SCB817Hu-10x96wellstestplate 10x96-wells test plate
EUR 6777.36
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Versican (VS) in serum, plasma and other biological fluids.

Human Versican (VS)CLIA Kit

SCB817Hu-1x48wellstestplate 1x48-wells test plate
EUR 663.31
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Versican (VS) in serum, plasma and other biological fluids.

Human Versican (VS)CLIA Kit

SCB817Hu-1x96wellstestplate 1x96-wells test plate
EUR 896.16
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Versican (VS) in serum, plasma and other biological fluids.

Human Versican (VS)CLIA Kit

SCB817Hu-5x96wellstestplate 5x96-wells test plate
EUR 3672.72
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Versican (VS) in serum, plasma and other biological fluids.

Human Versican (VS) CLIA Kit

4-SCB817Hu
  • EUR 6837.60
  • EUR 3673.20
  • EUR 896.40
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Human Versican (VS)Serum, plasma and other biological fluids

Human Versican (VS) ELISA Kit

SEB817Hu-10x96wellstestplate 10x96-wells test plate
EUR 5402.92
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Versican (VS) in serum, plasma, tissue homogenates and other biological fluids.

Human Versican (VS) ELISA Kit

SEB817Hu-1x48wellstestplate 1x48-wells test plate
EUR 550.13
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Versican (VS) in serum, plasma, tissue homogenates and other biological fluids.

Human Versican (VS) ELISA Kit

SEB817Hu-1x96wellstestplate 1x96-wells test plate
EUR 734.46
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Versican (VS) in serum, plasma, tissue homogenates and other biological fluids.

Human Versican (VS) ELISA Kit

SEB817Hu-5x96wellstestplate 5x96-wells test plate
EUR 2945.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Versican (VS) in serum, plasma, tissue homogenates and other biological fluids.

Human Versican (VS) ELISA Kit

4-SEB817Hu
  • EUR 5463.60
  • EUR 2886.00
  • EUR 735.60
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Versican (VS) in samples from serum, plasma, tissue homogenates and other biological fluids with no significant corss-reactivity with analogues from other species.

Mouse Versican (VS) ELISA Kit

SEB817Mu-10x96wellstestplate 10x96-wells test plate
EUR 5552.14
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Versican (VS) in serum, plasma, tissue homogenates and other biological fluids.

Mouse Versican (VS) ELISA Kit

SEB817Mu-1x48wellstestplate 1x48-wells test plate
EUR 562.42
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Versican (VS) in serum, plasma, tissue homogenates and other biological fluids.

Mouse Versican (VS) ELISA Kit

SEB817Mu-1x96wellstestplate 1x96-wells test plate
EUR 752.02
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Versican (VS) in serum, plasma, tissue homogenates and other biological fluids.

Mouse Versican (VS) ELISA Kit

SEB817Mu-5x96wellstestplate 5x96-wells test plate
EUR 3024.07
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Versican (VS) in serum, plasma, tissue homogenates and other biological fluids.

Mouse Versican (VS) ELISA Kit

4-SEB817Mu
  • EUR 5612.40
  • EUR 2965.20
  • EUR 752.40
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Versican (VS) in samples from serum, plasma, tissue homogenates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Versican(VS)ELISA Kit

QY-E03741 96T
EUR 433.2

Human Versican ELISA Kit (VS)

RK02510 96 Tests
EUR 625.2

Mouse Versican ELISA Kit (VS)

RK03285 96 Tests
EUR 625.2

VS-5584 (SB2343)

A3927-10 10 mg
EUR 226.8
Description: VS-5584 (SB2343), a purine analog, is a novel small-molecule inhibitor of both mammalian target of rapamycin (mTOR) kinase and all class I phosphoinostide 3-kinase (PI3K) isoforms that ATP-competitively inhibits the activity of mTOR, PI3K?, PI3K?, PI3K? and PI3K?.

VS-5584 (SB2343)

A3927-5 5 mg
EUR 184.8
Description: VS-5584 (SB2343), a purine analog, is a novel small-molecule inhibitor of both mammalian target of rapamycin (mTOR) kinase and all class I phosphoinostide 3-kinase (PI3K) isoforms that ATP-competitively inhibits the activity of mTOR, PI3K?, PI3K?, PI3K? and PI3K?.

VS-5584 (SB2343)

A3927-5.1 10 mM (in 1mL DMSO)
EUR 196.8
Description: VS-5584 (SB2343), a purine analog, is a novel small-molecule inhibitor of both mammalian target of rapamycin (mTOR) kinase and all class I phosphoinostide 3-kinase (PI3K) isoforms that ATP-competitively inhibits the activity of mTOR, PI3K?, PI3K?, PI3K? and PI3K?.

VS-5584 (SB2343)

A3927-50 50 mg
EUR 616.8
Description: VS-5584 (SB2343), a purine analog, is a novel small-molecule inhibitor of both mammalian target of rapamycin (mTOR) kinase and all class I phosphoinostide 3-kinase (PI3K) isoforms that ATP-competitively inhibits the activity of mTOR, PI3K?, PI3K?, PI3K? and PI3K?.

VS-5584 (SB2343)

A3927-S Evaluation Sample
EUR 97.2
Description: VS-5584 (SB2343), a purine analog, is a novel small-molecule inhibitor of both mammalian target of rapamycin (mTOR) kinase and all class I phosphoinostide 3-kinase (PI3K) isoforms that ATP-competitively inhibits the activity of mTOR, PI3K?, PI3K?, PI3K? and PI3K?.

Recombinant Versican (VS)

4-RPB817Hu01
  • EUR 550.08
  • EUR 271.20
  • EUR 1732.80
  • EUR 657.60
  • EUR 1195.20
  • EUR 444.00
  • EUR 4152.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Versican expressed in: E.coli

Recombinant Versican (VS)

4-RPB817Mu01
  • EUR 601.69
  • EUR 284.40
  • EUR 1926.34
  • EUR 722.11
  • EUR 1324.22
  • EUR 477.60
  • EUR 4635.84
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Versican expressed in: E.coli

NucView 488 and MitoView 633 Apoptosis Assay Kit (100 assays)

30062 1KIT
EUR 514.8
Description: Minimum order quantity: 1 unit of 1KIT

ELISA kit for Human VS (Versican)

ELK2206 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Versican from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Mouse VS (Versican)

ELK3294 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Versican from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Frit Kit

FRIT-KIT 1each
EUR 148.8
Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool.

Mouse Tumor Necrosis Factor Alpha (TNF-alpha) Detection Assay Kit

6701 1 kit
EUR 580.26
Description: Mouse Tumor Necrosis Factor Alpha (TNF-alpha) Detection Assay Kit

Rat Tumor Necrosis Factor Alpha (TNF-alpha) Detection Assay Kit

6901 1 kit
EUR 580.26
Description: Rat Tumor Necrosis Factor Alpha (TNF-alpha) Detection Assay Kit

Column Packing Kit

PACK-KIT 1pack
EUR 1242
Description: Column packing kit for pressure cells. Includes: HPREG regulator, TBNG10 tubing, CAP-75 capillary, and STRB5X2 stir bar.

NucView 488 and RedDot 2 Apoptosis & Necrosis Kit (100 assays)

30072 1KIT
EUR 458.4
Description: Minimum order quantity: 1 unit of 1KIT

Goat Tumor necrosis factor related apoptosis inducing ligand ELISA kit

E06T0023-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Goat Tumor necrosis factor related apoptosis inducing ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Tumor necrosis factor related apoptosis inducing ligand ELISA kit

E06T0023-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Goat Tumor necrosis factor related apoptosis inducing ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Tumor necrosis factor related apoptosis inducing ligand ELISA kit

E06T0023-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Goat Tumor necrosis factor related apoptosis inducing ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Tumor necrosis factor related apoptosis inducing ligand ELISA kit

E04T0023-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rabbit Tumor necrosis factor related apoptosis inducing ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Tumor necrosis factor related apoptosis inducing ligand ELISA kit

E04T0023-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rabbit Tumor necrosis factor related apoptosis inducing ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Tumor necrosis factor related apoptosis inducing ligand ELISA kit

E04T0023-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rabbit Tumor necrosis factor related apoptosis inducing ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Tumor necrosis factor related apoptosis inducing ligand ELISA kit

E03T0023-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Mouse Tumor necrosis factor related apoptosis inducing ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Tumor necrosis factor related apoptosis inducing ligand ELISA kit

E03T0023-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Mouse Tumor necrosis factor related apoptosis inducing ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Tumor necrosis factor related apoptosis inducing ligand ELISA kit

E03T0023-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Mouse Tumor necrosis factor related apoptosis inducing ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Tumor necrosis factor related apoptosis inducing ligand ELISA kit

E08T0023-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Canine Tumor necrosis factor related apoptosis inducing ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Tumor necrosis factor related apoptosis inducing ligand ELISA kit

E08T0023-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Canine Tumor necrosis factor related apoptosis inducing ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Tumor necrosis factor related apoptosis inducing ligand ELISA kit

E08T0023-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Canine Tumor necrosis factor related apoptosis inducing ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Tumor necrosis factor related apoptosis inducing ligand ELISA kit

E09T0023-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Monkey Tumor necrosis factor related apoptosis inducing ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Tumor necrosis factor related apoptosis inducing ligand ELISA kit

E09T0023-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Monkey Tumor necrosis factor related apoptosis inducing ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Tumor necrosis factor related apoptosis inducing ligand ELISA kit

E09T0023-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Monkey Tumor necrosis factor related apoptosis inducing ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Tumor necrosis factor related apoptosis inducing ligand ELISA kit

E02T0023-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rat Tumor necrosis factor related apoptosis inducing ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Tumor necrosis factor related apoptosis inducing ligand ELISA kit

E02T0023-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rat Tumor necrosis factor related apoptosis inducing ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Tumor necrosis factor related apoptosis inducing ligand ELISA kit

E02T0023-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rat Tumor necrosis factor related apoptosis inducing ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Tumor necrosis factor related apoptosis inducing ligand ELISA kit

E01T0023-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Human Tumor necrosis factor related apoptosis inducing ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Tumor necrosis factor related apoptosis inducing ligand ELISA kit

E01T0023-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Human Tumor necrosis factor related apoptosis inducing ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Tumor necrosis factor related apoptosis inducing ligand ELISA kit

E01T0023-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Human Tumor necrosis factor related apoptosis inducing ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Tumor necrosis factor related apoptosis inducing ligand ELISA kit

E07T0023-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Porcine Tumor necrosis factor related apoptosis inducing ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Tumor necrosis factor related apoptosis inducing ligand ELISA kit

E07T0023-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Porcine Tumor necrosis factor related apoptosis inducing ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Tumor necrosis factor related apoptosis inducing ligand ELISA kit

E07T0023-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Porcine Tumor necrosis factor related apoptosis inducing ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Cell Meter™ Caspase 8 Activity Apoptosis Assay Kit *Green Fluorescence*

22798 200 Tests
EUR 262.8

Cell Meter™ Caspase 9 Activity Apoptosis Assay Kit *Green Fluorescence*

22799 200 Tests
EUR 367.2

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