PRE-GMP rHu GM-CSF, Molgramostim-Leukoma
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GM-CSF (Granulocyte-Macrophage Colony-Stimulating Factor) GMP, CF |
PR15123CF |
Neuromics |
50 ug |
EUR 2266.8 |
GM-CSF/CSF2 |
E21-C79 |
EnoGene |
10ug |
EUR 411.6 |
Recombinant Human Granulocyte Macrophage Colony Stimlating Factor (rHu GM-CSF) |
70203 |
SAB |
20ul |
EUR 235 |
|
Description: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 0.1 ng/ml, corresponding to a specific activity of > 1.0 × 107 IU/mg. |
Recombinant Human Granulocyte Macrophage-Colony Stimulating Factor (rHu GM-CSF) |
AK8341-0150 |
Akron Biotech |
150ug |
EUR 2220 |
GM - CSF Rat |
PR27071 |
Neuromics |
2 ug |
EUR 177.6 |
GM - CSF Sf9 |
PR27072 |
Neuromics |
2 ug |
EUR 177.6 |
GM CSF, Sf9 |
cyt-416 |
ProSpec Tany |
2µg |
EUR 60 |
Description: Recombinant Human Granulocyte Macrophage-Colony Stimulating Factor, Sf9 |
GM CSF, His |
cyt-477 |
ProSpec Tany |
5µg |
EUR 60 |
Description: Recombinant Human Granulocyte Macrophage-Colony Stimulating Factor, His Tag |
GM - CSF Human |
PR27068 |
Neuromics |
2 ug |
EUR 229.2 |
GM - CSF Mouse |
PR27074 |
Neuromics |
2 ug |
EUR 229.2 |
GM - CSF Human Pichia |
PR27070 |
Neuromics |
2 ug |
EUR 177.6 |
GM CSF Recombinant Protein |
96-356 |
ProSci |
0.02 mg |
EUR 500.1 |
Description: Granulocyte-macrophage colony-stimulating factor (GM-CSF) is also known as Colony stimulating factor 2 (granulocyte-macrophage), is a cytokine initially characterized by its ability to induce colonies of granulocytes and macrophages from myeloid progenitor cells, and is secreted by macrophages, T cells, mast cells, endothelial cells and fibroblasts. GM-CSF is a cytokine that functions as a white blood cell growth factor. GM-CSF stimulates stem cells to produce granulocytes (neutrophils, eosinophils, and basophils) and monocytes. Monocytes exitthe circulation and migrate into tissue, whereupon they mature into macrophages and dendritic cells. Thus, it is part of the immune/inflammatory cascade, by which activation of a small number of macrophages can rapidly lead to an increase in their numbers, a process crucial for fighting infection. The active form of the protein is found extracellularly as a homodimer. Human GM-CSF glycosylated in its mature form. As a part of the immune/inflammatory cascade, GM-CSF promotes Th1 biased immune response, angiogenesis, allergic inflammation, and the development of autoimmunity, and thus worthy of consideration for therapeutic target. GM-CSF has also recently been evaluated in clinical trials for its potential as a vaccine adjuvant in HIV-infected patients. The preliminary results have been promising. GM-CSF is also used as a medication to stimulate the production of white blood cells following chemotherapy. |
GM-CSF |
E21-003 |
EnoGene |
10ug |
EUR 411.6 |
GM-CSF |
E21-J46 |
EnoGene |
10ug |
EUR 411.6 |
GM-CSF |
E8ER1909-78 |
EnoGene |
100ul |
EUR 275 |
Description: Available in various conjugation types. |
Anti-GM-CSF/CSF2 Antibody |
PB9003 |
BosterBio |
100ug/vial |
EUR 400.8 |
Anti-GM-CSF/CSF2 Antibody |
PA1456 |
BosterBio |
100ug/vial |
EUR 352.8 |
Recombinant Mouse GM-CSF/CSF2 |
CK02-10ug |
Novoprotein |
10ug |
EUR 242.4 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl, pH7.4. |
Recombinant Mouse GM-CSF/CSF2 |
CK02-1mg |
Novoprotein |
1mg |
EUR 2983.2 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl, pH7.4. |
Recombinant Mouse GM-CSF/CSF2 |
CK02-500ug |
Novoprotein |
500ug |
EUR 1935.6 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl, pH7.4. |
Recombinant Mouse GM-CSF/CSF2 |
CK02-50ug |
Novoprotein |
50ug |
EUR 595.2 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl, pH7.4. |
Recombinant Human GM-CSF (CSF2) |
Z100275 |
ABM |
20 µg |
EUR 85 |
Description: GM-CSF is a hematopoietic growth factor that is produced by endothelial cells, monocytes, fibroblasts and T-lymphocytes following their activation by antigens or mitogens. GM-CSF stimulates the development of macrophages and neutrophils and plays a role in the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. Approximately 90% of the secreted colony stimulating activities are due to GM-CSF. While non-glycosylated and glycosylated GM-CSF show similar activities in vitro, fully glycosylated GM-CSF is biologically more active in vivo compared to its non-glycosylated counterpart. Human and murine GM-CSF are species-specific and therefore, exhibit no cross-reactivity. Recombinant Human GM-CSF is a non-glycosylated, monomeric protein that contains intra-chain disulfide bonds. |
Recombinant Human GM-CSF (CSF2) |
Z100277 |
ABM |
100 µg |
EUR 210 |
Description: GM-CSF is a hematopoietic growth factor that is produced by endothelial cells, monocytes, fibroblasts and T-lymphocytes following their activation by antigens or mitogens. GM-CSF stimulates the development of macrophages and neutrophils and plays a role in the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. Approximately 90% of the secreted colony stimulating activities are due to GM-CSF. While non-glycosylated and glycosylated GM-CSF show similar activities in vitro, fully glycosylated GM-CSF is biologically more active in vivo compared to its non-glycosylated counterpart. Human and murine GM-CSF are species-specific and therefore, exhibit no cross-reactivity. Recombinant Human GM-CSF is a non-glycosylated, monomeric protein that contains intra-chain disulfide bonds. |
Recombinant Human GM-CSF (CSF2) |
Z100279 |
ABM |
10 x 100 µg (Z100277 x 10) |
EUR 1980 |
Description: GM-CSF is a monomeric protein of 127 amino acids with two glycosylation sites. The protein is synthesized as a precursor of 144 amino acids, which included a hydrophobic secretory signal sequence at the amino terminal end. The sugar moiety is not required for the full spectrum of biological activities. Non-glycosylated and glycosylated GM-CSF show the same activities in vitro. Fully glycosylated GM-CSF is biologically more active in vivo than the non-glycosylated protein. This protein is secreted together with other factors by T cells and macrophages following cell activation by antigens or mitogens. Approximately 90% of the secreted colony stimulating activities are due to GM-CSF. |
Recombinant Mouse GM-CSF (CSF2) |
Z200075 |
ABM |
20 µg |
EUR 190 |
Description: GM-CSF is a monomeric cytokine with two glycosylation sites that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. CSF2 is secreted together with other factors by T cells and macrophages following cell activation by antigens or mitogens. The signalling ‘GM-CSF:receptor’ complex is a dodecamer of two hexamers of two alpha, two beta, and two ligand subunits. While non-glycosylated and glycosylated GM-CSF show similar activities in vitro, fully glycosylated GM-CSF is biologically more active in vivo. Recombinant Mouse CSF2 is a non-glycosylated, monomeric protein. |
Recombinant Mouse GM-CSF (CSF2) |
Z200077 |
ABM |
5 x 20 µg (Z200075 x 5) |
EUR 850 |
Description: GM-CSF is a monomeric cytokine with two glycosylation sites that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. CSF2 is secreted together with other factors by T cells and macrophages following cell activation by antigens or mitogens. The signalling ‘GM-CSF:receptor’ complex is a dodecamer of two hexamers of two alpha, two beta, and two ligand subunits. While non-glycosylated and glycosylated GM-CSF show similar activities in vitro, fully glycosylated GM-CSF is biologically more active in vivo. Recombinant Mouse CSF2 is a non-glycosylated, monomeric protein. |
Recombinant Mouse GM-CSF (CSF2) |
Z200079 |
ABM |
1.0 mg |
EUR 4350 |
Description: GM-CSF is a monomeric protein of 127 amino acids with two glycosylation sites. The protein is synthesized as a precursor of 144 amino acids, which included a hydrophobic secretory signal sequence at the aminoterminal end. The sugar moiety is not required for the full spectrum of biological activities. Non-glycosylated and glycosylated GM-CSF show the same activities in vitro. Fully glycosylated GM-CSF is biologically more active in vivo than the non- glycosylated protein. This protein is secreted together with other factors by T cells and macrophages following cell activation by antigens or mitogens. Approximately 90% of the secreted colony stimulating activities are due to GM-CSF. |
Recombinant Mouse GM-CSF/CSF2 |
AP76135 |
SAB |
1mg |
EUR 3489 |
|
PRE-GMP rHu GM-CSF, Molgramostim-Leukoma