PD-0325901
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PD 0325901 |
MBS696352-5x25mg |
MyBiosource |
5x25mg |
EUR 1410 |
EZSolution? PD-0325901, Sterile-Filtered |
1990-1 |
Biovision |
each |
EUR 326.4 |
PD-325901, Free Base (PD 0325901, MEK1/2 Inhibitor III) |
MBS6061791-10mg |
MyBiosource |
10(mg |
EUR 255 |
PD-325901, Free Base (PD 0325901, MEK1/2 Inhibitor III) |
MBS6061791-25mg |
MyBiosource |
25mg |
EUR 450 |
PD-325901, Free Base (PD 0325901, MEK1/2 Inhibitor III) |
MBS6061791-5x25mg |
MyBiosource |
5x25mg |
EUR 1865 |
PD150606 (PD 150606; PD-150606) |
MBS131512-100mg |
MyBiosource |
100mg |
EUR 1495 |
PD-1/PD-L1 inhibitor 2 |
B6023-25 |
ApexBio |
25 mg |
EUR 268 |
|
Description: Apoptosis|PD-1/PD-L1 interaction#Apoptosis |
PD-1/PD-L1 inhibitor 2 |
B6023-5 |
ApexBio |
5 mg |
EUR 84 |
|
Description: Apoptosis|PD-1/PD-L1 interaction#Apoptosis |
PD-1/PD-L1 inhibitor 1 |
B6172-25 |
ApexBio |
25 mg |
EUR 278.4 |
|
Description: Apoptosis|PD-1/PD-L1 interaction |
PD-1/PD-L1 inhibitor 1 |
B6172-5 |
ApexBio |
5 mg |
EUR 82.4 |
|
Description: Apoptosis|PD-1/PD-L1 interaction |
PD-1/PD-L1 Inhibitor 3 |
B6191-1 |
ApexBio |
1 mg |
EUR 248.8 |
|
Description: Apoptosis|PD-1/PD-L1 interaction |
PD-1/PD-L1 Inhibitor 3 |
B6191-5 |
ApexBio |
5 mg |
EUR 837.6 |
|
Description: Apoptosis|PD-1/PD-L1 interaction |
PD-1/PD-L1 Inhibitor 2 |
B1050-25 |
Biovision |
each |
EUR 679.2 |
PD-1/PD-L1 Inhibitor 2 |
B1050-5 |
Biovision |
each |
EUR 242.4 |
PD-1/PD-L1 Inhibitor 1 |
B1213-25 |
Biovision |
each |
EUR 679.2 |
PD-1/PD-L1-IN-31 |
HY-149356 |
MedChemExpress |
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Description: PD-1/PD-L1-IN-31 is a PD-1/PD-L1 inhibitor (IC50=2.2 nM). PD-1/PD-L1-IN-31 promotes secretion of the IFN-γ, and induces immune activity of peripheral blood mononuclear cells (PBMCs) to inhibits tumor cells[1]. |
PD-1/PD-L1-IN-29 |
HY-152240 |
MedChemExpress |
1 mg |
EUR 919.93 |
Description: PD-1/PD-L1-IN-29 (S4-1) is a potent PD-1/PD-L1 inhibitor with an IC50 value of 6.1 nM. PD-1/PD-L1-IN-29 binds PD-L1 and disrupts PD-1/PD-L1 interactions, induces PD-L1 dimerization and internalization, improves its localization to the endoplasmic reticulum, and promotes PD-L1 entry into the endoplasmic reticulum. PD-1/PD-L1-IN-29 has anticancer activity[1]. |
PD-1/PD-L1-IN 3 |
HY-103048 |
MedChemExpress |
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Description: PD-1/PD-L1-IN 3, a macrocyclic peptide, is a potent and selective inhibitor of the PD-1/PD-L1 and CD80/PD-L1 interactions extracted from patent WO2014151634A1, compound No.1. PD-1/PD-L1-IN 3 interferes with PD-L1 binding to PD-1 and CD80 by binding to PD-L1, with IC50s of 5.60 nM and 7.04 nM, respectively. PD-1/PD-L1-IN 3 can be used for the research of various diseases, including cancer and infectious diseases[1]. |
PD-1/PD-L1-IN-34 |
HY-154869 |
MedChemExpress |
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Description: PD-1/PD-L1-IN-34 (Compound (1S,2S)-A25) inhibits PD-1/PD-L1 interaction (IC50=0.029 μM), with a selected binding affinity with PD-L1 (KD=0.1554 μM). PD-1/PD-L1-IN-34 inhibits tumor growth by activating the immune microenvironment[1]. |
PD-1/PD-L1-IN-32 |
HY-155740 |
MedChemExpress |
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Description: PD-1/PD-L1-IN-32 (compound A56) is a potent PD-1/PD-L1 inhibitor (IC50=2.4 nM), with anticancer activity. PD-1/PD-L1-IN-32 significantly inhibits tumor growth in hPD-L1 MC38 humanized mouse model, without obvious toxicity against mouse normal ability[1]. |
PD-1/PD-L1-IN-33 |
HY-155959 |
MedChemExpress |
10 mg |
EUR 1623.4 |
Description: PD-1/PD-L1-IN-33 (Compound N11) is a PD-1/PD-L1 inhibitor. PD-1/PD-L1-IN-33 inhibits PD-1 and PD-L1 interaction with an IC50: 6.3 nM. PD-1/PD-L1-IN-33 promotes T-cell proliferation, activation, and infiltration into tumor spheres. PD-1/PD-L1-IN-33 has immunomodulatory and anticancer activity[1]. |
PD-1/PD-L1-IN-36 |
HY-163041 |
MedChemExpress |
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Description: PD-1/PD-L1-IN-36 (Compound 2k) is a PD-1/PD-L1 complex inhibitor (IC50: 15 nM). PD-1/PD-L1-IN-36 can be used for research of cancer immunotherapy[1]. |
PD-1/PD-L1-IN 5 |
HY-129172A |
MedChemExpress |
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Description: PD-1/PD-L1-IN 5 is a PD-1/PD-L1 protein/protein interaction inhibitor extracted from patent WO2017222976A1, compound Example 1, has an IC50 of ≤100 nM[1]. |
PD-1/PD-L1-IN 6 |
HY-130625 |
MedChemExpress |
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Description: PD-1/PD-L1-IN 6 (compound A13) is a potent PD-1/PD-L1 interaction inhibitor, with an IC50 of 132.8 nM. PD-1/PD-L1-IN 6 exhibits outstanding immunoregulatory activity. PD-1/PD-L1-IN 6 significantly elevates interferon-γ secretion in a Hep3B/OS-8/hPD-L1 and CD3 T cell co-culture model, without significant toxic effect. PD-1/PD-L1-IN 6 restores the immune response in a T cell-tumor co-culture model[1]. |
PD-1/PD-L1-IN-NP19 |
HY-131347 |
MedChemExpress |
10 mg |
EUR 1948.08 |
Description: PD-1/PD-L1-IN-NP19 is a PD-1/PD-L1 inhibitor, with an IC50 of 12.5 nM for human PD-1/PD-L1 interaction. PD-1/PD-L1-IN-NP19 could activate the immune microenvironment in tumor, which may contribute to its antitumor effects[1]. |
PD-1/PD-L1-IN-9 |
HY-132192 |
MedChemExpress |
10 mg |
EUR 984.86 |
Description: PD-1/PD-L1-IN-9 is a potent and orally active inhibitor of PD-1/PD-L1 interaction, with an IC50 of 3.8 nM. PD-1/PD-L1-IN-9 can enhance the killing activity of tumor cells by immune cells. PD-1/PD-L1-IN-9 also exhibits significant in vivo antitumor activity in a CT26 mouse model[1]. |
PD-1/PD-L1-IN-10 |
HY-132202 |
MedChemExpress |
10 mg |
EUR 779.23 |
Description: PD-1/PD-L1-IN-10 (compound B2) is an orally active PD-1/PD-L1 inhibitor (IC50 of 2.7 nM) with potent anticancer efficacy[1]. |
PD-1/PD-L1-IN-13 |
HY-145239 |
MedChemExpress |
1 mg |
EUR 3517.37 |
Description: PD-1/PD-L1-IN-13 (Compound 43) is a potent immune checkpoint PD-1/PD-L1 inhibitor with an IC50 value of 10.2 nM. PD-1/PD-L1-IN-13 promots CD8+ T cell activation and delays the tumor growth in the Hepa1-6 syngeneic mouse model[1]. |
PD-1/PD-L1-IN-18 |
HY-145768 |
MedChemExpress |
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Description: PD-1/PD-L1-IN-18 (Compound L31) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-18 blocks PD-1/PD-L1 with the IC50 of 1.054 μM. Antitumor Activity[1]. |
PD-1/PD-L1-IN-19 |
HY-145770 |
MedChemExpress |
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Description: PD-1/PD-L1-IN-19 (Example 22) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-19 blocks PD-1/PD-L1 with the IC50 of 62.3 nM. PD-1/PD-L1-IN-19 can be used for the research of cancers, infectious diseases and autoimmune diseases[1]. |
PD-1/PD-L1-IN-20 |
HY-145771 |
MedChemExpress |
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Description: PD-1/PD-L1-IN-20 (Example 21) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-20 blocks PD-1/PD-L1 with the IC50 of 5.29 nM. PD-1/PD-L1-IN-20 can be used for the research of cancers, infectious diseases and autoimmune diseases[1]. |
PD-1/PD-L1-IN-21 |
HY-145772 |
MedChemExpress |
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Description: PD-1/PD-L1-IN-21 (Example 22) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-21 blocks PD-1/PD-L1 with the IC50 of 4.99 μM. PD-1/PD-L1-IN-21 can be used for the research of cancers, infectious diseases and autoimmune diseases[1]. |
PD-1/PD-L1-IN-22 |
HY-145773 |
MedChemExpress |
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Description: PD-1/PD-L1-IN-22 (Example 2) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-22 blocks PD-1/PD-L1 with the IC50 of 0.732 μM. PD-1/PD-L1-IN-22 can be used for the research of cancers, infectious diseases and autoimmune diseases[1]. |
PD-1/PD-L1-IN-23 |
HY-145774 |
MedChemExpress |
10 mg |
EUR 4058.51 |
Description: PD-1/PD-L1-IN-23 is a potent and orally active inhibitor of PD-1/PD-L1. PD-1/PD-L1-IN-23 is an ester proagent of L7. L7 is a benzo[c][1,2,5]oxadiazole derivative and biologically evaluated as inhibitors of PD-L1. PD-1/PD-L1-IN-23 displays significant antitumor effects in tumor models of syngeneic and PD-L1 humanized mice[1]. |
PD-1/PD-L1-IN-27 |
HY-146740 |
MedChemExpress |
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Description: PD-1/PD-L1-IN-27 is a potent PD-1/PD-L1 inhibitor with an IC50 value of 134 nM. PD-1/PD-L1-IN-27 shows antitumor effects with low T cell cytotoxicity. PD-1/PD-L1-IN-27 has the ability to activate CD8+ T cells and reduces T cell exhaustion[1]. |
PD-1/PD-L1-IN-28 |
HY-148305 |
MedChemExpress |
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Description: PD-1/PD-L1-IN-28 (compound 3) is an immune checkpoint inhibitor of PD-1/PD-L1 signaling pathway (IC50=0.744 µM). PD-1/PD-L1-IN-28 shows good research potential in tumor immunity[1]. |
PD-1/PD-L1-IN-25 |
HY-143305 |
MedChemExpress |
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Description: PD-1/PD-L1-IN-25 (compound D2) is an inhibitor of PD-1/PD-L1 interaction with an IC50 value of 16.17 nM. PD-1/PD-L1-IN-25 activates the antitumor immunity of T cells efficiently in PBMCs. PD-1/PD-L1-IN-25 can be used for the research of cancer[1]. |
PD-1/PD-L1-IN-14 |
HY-144258 |
MedChemExpress |
10 mg |
EUR 2543.33 |
Description: PD-1/PD-L1-IN-14 (compound 17) is a bifunctional inhibitor of PD-1/PD-L1 interactions, with an IC50 of 27.8 nM. PD-1/PD-L1-IN-14 (compound 17) inhibits PD-1/PD-L1 interactions and promotes dimerization, internalization, and degradation of PD-L1[1]. |
PD-1/PD-L1-IN-15 |
HY-144442 |
MedChemExpress |
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Description: PD-1/PD-L1-IN-15 (Compound M17) is a potent inhibitor of PD-1/PD-L1 with an IC50 value of 60.1 nM. PD-1/PD-L1-IN-15 has the potential for the research of tumor immunoresearch[1]. |
PD-1/PD-L1-IN-16 |
HY-144443 |
MedChemExpress |
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Description: PD-1/PD-L1-IN-16 (Compound M23) is a potent inhibitor of PD-1/PD-L1 with an IC50 value of 53.2 nM. PD-1/PD-L1-IN-16 has the potential for the research of tumor immunoresearch[1]. |
PD-1/PD-L1-IN-17 |
HY-144447 |
MedChemExpress |
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Description: PD-1/PD-L1-IN-17 (Compound P20) is a potent inhibitor of PD-1/PD-L1 with an IC50 value of 26.8 nM. PD-1/PD-L1-IN-17 is a promising lead compound for the development of inhibitors of the PD-1/PD-L1 interaction. PD-1/PD-L1-IN-17 has the potential for the research of cancer diseases[1]. |
PD-1/PD-L1-IN-24 |
HY-144649 |
MedChemExpress |
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Description: PD-1/PD-L1-IN-24 is a highly potent PD-1/PD-L1 inhibitor with IC50 value of 1.57 nM. PD-1/PD-L1-IN-24 can restore T-cell function at the cellular level by significantly elevating the IFN-γ level. PD-1/PD-L1-IN-24 has low toxicity on the PBMCs[1]. |
PD-1/PD-L1-IN-26 |
HY-144746 |
MedChemExpress |
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Description: PD-1/PD-L1-IN-26 (Compound II-14) is a potent inhibitor of PD-1/PD-L1 with an IC50 of 0.0380 μM. PD-1/PD-L1-IN-26 activates the immune microenvironment by promoting the infiltration of CD4+ T cells into tumor tissues. PD-1/PD-L1-IN-26 has the potential for the research of cancer diseases[1]. |
PD-1/PD-L1-IN-10 |
MBS5786462-10mg |
MyBiosource |
10(mg |
EUR 250 |
PD-1/PD-L1-IN-10 |
MBS5786462-2mg |
MyBiosource |
2(mg |
EUR 180 |
PD-1/PD-L1-IN-10 |
MBS5786462-5mg |
MyBiosource |
5(mg |
EUR 195 |
PD-1/PD-L1-IN-9 |
MBS5801395-1mg |
MyBiosource |
1(mg |
EUR 225 |
PD-1/PD-L1-IN-9 |
MBS5801395-5mg |
MyBiosource |
5(mg |
EUR 345 |
PD-1/PD-L1-IN-NP19 |
MBS5785098-10mg |
MyBiosource |
10mg |
EUR 555 |
PD-1/PD-L1-IN-NP19 |
MBS5785098-25mg |
MyBiosource |
25mg |
EUR 1350 |
PD-1/PD-L1-IN-NP19 |
MBS5785098-50mg |
MyBiosource |
50(mg |
EUR 1520 |
PD-1/PD-L1-IN-NP19 |
MBS5785098-5mg |
MyBiosource |
5(mg |
EUR 375 |
PD-1/PD-L1 inhibitor 1 |
MBS578522-10mg |
MyBiosource |
10mg |
EUR 250 |
PD-1/PD-L1 inhibitor 1 |
MBS578522-25mg |
MyBiosource |
25mg |
EUR 375 |
PD-1/PD-L1 inhibitor 1 |
MBS578522-2mg |
MyBiosource |
2mg |
EUR 160 |
PD-1/PD-L1 inhibitor 1 |
MBS578522-50mg |
MyBiosource |
50mg |
EUR 510 |
PD-1/PD-L1 inhibitor 1 |
MBS578522-5mg |
MyBiosource |
5mg |
EUR 190 |
PD-1/PD-L1-IN-25 |
T63329-10mg |
TargetMol Chemicals |
10mg |
Ask for price |
|
Description: PD-1/PD-L1-IN-25 |
PD-1/PD-L1-IN-25 |
T63329-1mg |
TargetMol Chemicals |
1mg |
Ask for price |
|
Description: PD-1/PD-L1-IN-25 |
PD-1/PD-L1-IN-25 |
T63329-50mg |
TargetMol Chemicals |
50mg |
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|
Description: PD-1/PD-L1-IN-25 |
PD-1/PD-L1-IN-25 |
T63329-5mg |
TargetMol Chemicals |
5mg |
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|
Description: PD-1/PD-L1-IN-25 |
PD-1/PD-L1-IN-22 |
T63607-10mg |
TargetMol Chemicals |
10mg |
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|
Description: PD-1/PD-L1-IN-22 |
PD-1/PD-L1-IN-22 |
T63607-1mg |
TargetMol Chemicals |
1mg |
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|
Description: PD-1/PD-L1-IN-22 |
PD-1/PD-L1-IN-22 |
T63607-50mg |
TargetMol Chemicals |
50mg |
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|
Description: PD-1/PD-L1-IN-22 |
PD-1/PD-L1-IN-22 |
T63607-5mg |
TargetMol Chemicals |
5mg |
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|
Description: PD-1/PD-L1-IN-22 |
PD-1/PD-L1-IN-15 |
T63614-10mg |
TargetMol Chemicals |
10mg |
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|
Description: PD-1/PD-L1-IN-15 |
PD-1/PD-L1-IN-15 |
T63614-1mg |
TargetMol Chemicals |
1mg |
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Description: PD-1/PD-L1-IN-15 |
PD-1/PD-L1-IN-15 |
T63614-50mg |
TargetMol Chemicals |
50mg |
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|
Description: PD-1/PD-L1-IN-15 |
PD-1/PD-L1-IN-15 |
T63614-5mg |
TargetMol Chemicals |
5mg |
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|
Description: PD-1/PD-L1-IN-15 |
PD-1/PD-L1-IN-16 |
T63948-10mg |
TargetMol Chemicals |
10mg |
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|
Description: PD-1/PD-L1-IN-16 |
PD-1/PD-L1-IN-16 |
T63948-1mg |
TargetMol Chemicals |
1mg |
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|
Description: PD-1/PD-L1-IN-16 |
PD-1/PD-L1-IN-16 |
T63948-50mg |
TargetMol Chemicals |
50mg |
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|
Description: PD-1/PD-L1-IN-16 |
PD-1/PD-L1-IN-16 |
T63948-5mg |
TargetMol Chemicals |
5mg |
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|
Description: PD-1/PD-L1-IN-16 |
PD-1/PD-L1-IN-20 |
T64086-10mg |
TargetMol Chemicals |
10mg |
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|
Description: PD-1/PD-L1-IN-20 |
PD-1/PD-L1-IN-20 |
T64086-1mg |
TargetMol Chemicals |
1mg |
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|
Description: PD-1/PD-L1-IN-20 |
PD-1/PD-L1-IN-20 |
T64086-50mg |
TargetMol Chemicals |
50mg |
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|
Description: PD-1/PD-L1-IN-20 |
PD-1/PD-L1-IN-20 |
T64086-5mg |
TargetMol Chemicals |
5mg |
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|
Description: PD-1/PD-L1-IN-20 |
PD-1/PD-L1-IN-NP19 |
T36900-10mg |
TargetMol Chemicals |
10mg |
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|
Description: PD-1/PD-L1-IN-NP19 |
PD-1/PD-L1-IN-NP19 |
T36900-1g |
TargetMol Chemicals |
1g |
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|
Description: PD-1/PD-L1-IN-NP19 |
PD-1/PD-L1-IN-NP19 |
T36900-1mg |
TargetMol Chemicals |
1mg |
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|
Description: PD-1/PD-L1-IN-NP19 |
PD-1/PD-L1-IN-NP19 |
T36900-50mg |
TargetMol Chemicals |
50mg |
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|
Description: PD-1/PD-L1-IN-NP19 |
PD-1/PD-L1-IN-NP19 |
T36900-5mg |
TargetMol Chemicals |
5mg |
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|
Description: PD-1/PD-L1-IN-NP19 |
PD-1/PD-L1-IN-14 |
T61929-10mg |
TargetMol Chemicals |
10mg |
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Description: PD-1/PD-L1-IN-14 |
PD-1/PD-L1-IN-14 |
T61929-1mg |
TargetMol Chemicals |
1mg |
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Description: PD-1/PD-L1-IN-14 |
PD-1/PD-L1-IN-14 |
T61929-50mg |
TargetMol Chemicals |
50mg |
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|
Description: PD-1/PD-L1-IN-14 |
PD-1/PD-L1-IN-14 |
T61929-5mg |
TargetMol Chemicals |
5mg |
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|
Description: PD-1/PD-L1-IN-14 |
PD-1/PD-L1-IN 6 |
T61968-10mg |
TargetMol Chemicals |
10mg |
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|
Description: PD-1/PD-L1-IN 6 |
PD-1/PD-L1-IN 6 |
T61968-50mg |
TargetMol Chemicals |
50mg |
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|
Description: PD-1/PD-L1-IN 6 |
PD-1/PD-L1-IN 5 |
T62193-10mg |
TargetMol Chemicals |
10mg |
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|
Description: PD-1/PD-L1-IN 5 |
PD-1/PD-L1-IN 5 |
T62193-50mg |
TargetMol Chemicals |
50mg |
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|
Description: PD-1/PD-L1-IN 5 |
PD-1/PD-L1-IN-17 |
T62501-10mg |
TargetMol Chemicals |
10mg |
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|
Description: PD-1/PD-L1-IN-17 |
PD-1/PD-L1-IN-17 |
T62501-1mg |
TargetMol Chemicals |
1mg |
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|
Description: PD-1/PD-L1-IN-17 |
PD-1/PD-L1-IN-17 |
T62501-50mg |
TargetMol Chemicals |
50mg |
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|
Description: PD-1/PD-L1-IN-17 |
PD-1/PD-L1-IN-17 |
T62501-5mg |
TargetMol Chemicals |
5mg |
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|
Description: PD-1/PD-L1-IN-17 |
PD-1/PD-L1-IN-10 |
T9616-10mg |
TargetMol Chemicals |
10mg |
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|
Description: PD-1/PD-L1-IN-10 |
PD-1/PD-L1-IN-10 |
T9616-50mg |
TargetMol Chemicals |
50mg |
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|
Description: PD-1/PD-L1-IN-10 |
PD-0325901