BIIB021 Free base

BIIB021 Free base

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BIIB021
A4058-50 50 mg
EUR 168
Description: Metabolism|HSP#Proteases|HSP

BIIB021
27046 5 mg
EUR 130
Description: BIIB021 is an orally available, synthetic small-molecule Hsp90 inhibitor. It binds in the ATP-binding pocket of Hsp90 (Ki = 1.7 ± 0.4 nM) and induces HER-2 degradation with an EC50 of 38 ± 10 nM in MCF-7 cells. It ncreases expression of the heat shock proteins Hsp90α and Hsp70, but has no effect on expression of the nonclient protein phosphatidylinositol 3-kinase p85 subunit. BIIB021 inhibits the proliferation of N87, MCF-7, and BT474 tumor cells with IC50 values of 0.06, 0.31, and 0.14 µM, respectively. It has significant antitumor activity in N87 stomach, BT474 breast, CWR22 prostate, U87 glioblastoma, SKOV3 ovarian, and Panc-1 pancreatic tumor xenograft models.

BIIB021
200505 10.0mg
EUR 150

BIIB021
abx188616-96tests 96 tests
EUR 118.75

BIIB021
HY-10212 50mg
EUR 250
Description: BIIB021 (CNF2024) is an orally active, fully synthetic inhibitor of HSP90 with a Ki and an EC50 of 1.7 nM and 38 nM, respectively[1].

BIIB021
MBS384528-100mg 100mg
EUR 430

BIIB021
MBS384528-10mg 10mg
EUR 170

BIIB021
MBS384528-1mLinDMSO 1mL(inDMSO)
EUR 145

BIIB021
MBS384528-50mg 50mg
EUR 300

BIIB021
MBS384528-5mg 5mg
EUR 145

BIIB021
MBS3606160-100mg 100mg
EUR 435

BIIB021
MBS3606160-10mg 10mg
EUR 225

BIIB021
MBS3606160-25mg 25mg
EUR 260

BIIB021
MBS3606160-50mg 50mg
EUR 340

BIIB021
MBS3606160-5mg 5mg
EUR 210

BIIB021
T2286-10mg 10mg Ask for price
Description: BIIB021

BIIB021
T2286-1g 1g Ask for price
Description: BIIB021

BIIB021
T2286-1mg 1mg Ask for price
Description: BIIB021

BIIB021
T2286-50mg 50mg Ask for price
Description: BIIB021

BIIB021
T2286-5mg 5mg Ask for price
Description: BIIB021

BIIB068
462609 50.0mg
EUR 950

Biib-021
abx188616-1g 1 g
EUR 910.8

BIIB068
HY-131342 10 mg
EUR 1130.97
Description: BIIB068 is a potent, selective, reversible and orally active BTK inhibitor with an IC50 of 1 nM and a Kd of 0.3 nM. BIIB068 shows more >400-fold selective for BTK than other kinases. BIIB068 has the potential for autoimmune diseases research[1].

BIIB091
HY-139984 10 mg
EUR 6764.18
Description: BIIB091 is a potent, selective, orally active and reversible BTK inhibitor, with an IC50 of <0.5 nM. BIIB091 binds the BTK protein to sequester TYR-551 into an inactive conformation with excellent affinity. BIIB091 can be used for the research of multiple sclerosis[1].

BIIB068
MBS5765268-10mg 10mg
EUR 310

BIIB068
MBS5765268-1mg 1mg
EUR 170

BIIB068
MBS5765268-25mg 25mg
EUR 515

BIIB068
MBS5765268-50mg 50mg
EUR 835

BIIB068
MBS5765268-5mg 5mg
EUR 240

BIIB091
MBS5800174-10mg 10mg
EUR 2020

BIIB091
MBS5800174-5mg 5(mg
EUR 1280

BIIB091
MBS5800174-5x10mg 5x10(mg
EUR 8930

BIIB-513
MBS5776535-5mg 5(mg
EUR 915

BIIB-513
MBS5776535-5x5mg 5x5(mg
EUR 3970

BIIB-021
MBS578035-100mg 100mg
EUR 305

BIIB-021
MBS578035-10mg 10mg
EUR 155

BIIB-021
MBS578035-25mg 25mg
EUR 185

BIIB-021
MBS578035-50mg 50mg
EUR 240

BIIB-021
MBS578035-5mg 5mg
EUR 140

BIIB-057
MBS5773557-5mg 5mg
EUR 915

BIIB-057
MBS5773557-5x5mg 5x5mg
EUR 3970

BIIB-513
T26808-10mg 10mg Ask for price
Description: BIIB-513

BIIB-513
T26808-1g 1g Ask for price
Description: BIIB-513

BIIB-513
T26808-1mg 1mg Ask for price
Description: BIIB-513

BIIB-513
T26808-50mg 50mg Ask for price
Description: BIIB-513

BIIB-513
T26808-5mg 5mg Ask for price
Description: BIIB-513

BIIB-057
T23790-10mg 10mg Ask for price
Description: BIIB-057

BIIB-057
T23790-1g 1g Ask for price
Description: BIIB-057

BIIB-057
T23790-1mg 1mg Ask for price
Description: BIIB-057

BIIB-057
T23790-50mg 50mg Ask for price
Description: BIIB-057

BIIB-057
T23790-5mg 5mg Ask for price
Description: BIIB-057

BIIB091
T39761-10mg 10mg Ask for price
Description: BIIB091

BIIB091
T39761-1g 1g Ask for price
Description: BIIB091

BIIB091
T39761-1mg 1mg Ask for price
Description: BIIB091

BIIB091
T39761-50mg 50mg Ask for price
Description: BIIB091

BIIB091
T39761-5mg 5mg Ask for price
Description: BIIB091

BIIB068
T9192-10mg 10mg Ask for price
Description: BIIB068

BIIB068
T9192-1g 1g Ask for price
Description: BIIB068

BIIB068
T9192-1mg 1mg Ask for price
Description: BIIB068

BIIB068
T9192-50mg 50mg Ask for price
Description: BIIB068

BIIB068
T9192-5mg 5mg Ask for price
Description: BIIB068

(Rac)-BIIB042
HY-103537 Get quote Ask for price
Description: (Rac)-BIIB042 (Compound 10) is an modulator of γ-Secretase. (Rac)-BIIB042 reduces Amyloid-β 42 level with an EC50 value of 0.39 µM. (Rac)-BIIB042 can be used for the study of Alzheimer's disease[1].

MLN2480 (BIIB-024)
MBS385162-10mg 10mg
EUR 345

MLN2480 (BIIB-024)
MBS385162-25mg 25mg
EUR 615

MLN2480 (BIIB-024)
MBS385162-50mg 50mg
EUR 985

MLN2480 (BIIB-024)
MBS385162-5mg 5mg
EUR 240

MLN2480 (BIIB-024)
MBS385162-5x50mg 5x50mg
EUR 4420

Vipadenant (BIIB-014)
MBS131433-100mg 100mg
EUR 1495

Vipadenant (BIIB-014)
MBS3840123-10mg 10mg
EUR 240

Vipadenant (BIIB-014)
MBS3840123-50mg 50mg
EUR 575

Vipadenant (BIIB-014)
MBS3840123-5mg 5mg
EUR 175

Vipadenant (BIIB-014)
MBS3840123-5x50mg 5x50mg
EUR 2570

P505-15 (PRT062607, BIIB057)
MBS385876-10mg 10mg
EUR 270

P505-15 (PRT062607, BIIB057)
MBS385876-1mLinDMSO 1mL(inDMSO)
EUR 230

P505-15 (PRT062607, BIIB057)
MBS385876-25mg 25mg
EUR 465

P505-15 (PRT062607, BIIB057)
MBS385876-50mg 50mg
EUR 750

P505-15 (PRT062607, BIIB057)
MBS385876-5mg 5mg
EUR 190

PRT062607 (P505-15, BIIB057) HCl
MBS577157-10mg 10mg
EUR 270

PRT062607 (P505-15, BIIB057) HCl
MBS577157-1mg 1mg
EUR 155

PRT062607 (P505-15, BIIB057) HCl
MBS577157-25mg 25mg
EUR 400

PRT062607 (P505-15, BIIB057) HCl
MBS577157-2mg 2mg
EUR 180

PRT062607 (P505-15, BIIB057) HCl
MBS577157-5mg 5mg
EUR 215

Anti-CLEC4C Reference Antibody (BIIB059)
E24CHA742 100 μg
EUR 225
Description: Available in various conjugation types.

BIIB 021
2291-25 each
EUR 483.6

BIIB 021
2291-5 each
EUR 170.4

BIIB 021
B384500 100mg
EUR 800
Description: 848695-25-0

BIIB 021
MBS132217-100mg 100mg
EUR 1065

BIIB 021
MBS132217-500mg 500mg
EUR 2775

BIIB 021
MBS6104269-50mg 50(mg
EUR 610

BIIB 021
MBS6104269-5x50mg 5x50mg
EUR 2600

I-37 free base (2359690-13-2(free base))
MBS5759495-10mg 10mg
EUR 470

I-37 free base (2359690-13-2(free base))
MBS5759495-1mg 1mg
EUR 210

I-37 free base (2359690-13-2(free base))
MBS5759495-25mg 25mg
EUR 780

I-37 free base (2359690-13-2(free base))
MBS5759495-50mg 50mg
EUR 1130

I-37 free base (2359690-13-2(free base))
MBS5759495-5mg 5mg
EUR 335

I-37 free base( 2359690-13-2(free base))
T8721L-10mg 10mg Ask for price
Description: I-37 free base( 2359690-13-2(free base))

I-37 free base( 2359690-13-2(free base))
T8721L-1g 1g Ask for price
Description: I-37 free base( 2359690-13-2(free base))

I-37 free base( 2359690-13-2(free base))
T8721L-1mg 1mg Ask for price
Description: I-37 free base( 2359690-13-2(free base))

I-37 free base( 2359690-13-2(free base))
T8721L-50mg 50mg Ask for price
Description: I-37 free base( 2359690-13-2(free base))

I-37 free base( 2359690-13-2(free base))
T8721L-5mg 5mg Ask for price
Description: I-37 free base( 2359690-13-2(free base))

EDC free base
GM6988 5g
EUR 116.06

TMB free base
TB0954 1g
EUR 85.06

S107 free base
530577 100.0mg
EUR 750

NG25 free base
562503 5.0mg
EUR 485

R406 (free base)
A5880-100 100 mg
EUR 800
Description: Tyrosine Kinase|Spleen Tyrosine Kinase (Syk)

R406 (free base)
A5880-25 25 mg
EUR 320
Description: Tyrosine Kinase|Spleen Tyrosine Kinase (Syk)

R406 (free base)
A5880-5 5 mg
EUR 80
Description: Tyrosine Kinase|Spleen Tyrosine Kinase (Syk)

R406 (free base)
A5880-5.1 10 mM (in 1mL DMSO)
EUR 148
Description: Tyrosine Kinase|Spleen Tyrosine Kinase (Syk)

R406 (free base)
A5880-S Evaluation Sample
EUR 24
Description: Tyrosine Kinase|Spleen Tyrosine Kinase (Syk)

THZ1 (Free base)
9664-25 each
EUR 1227.6

THZ1 (Free base)
9664-5 each
EUR 352.8

K201 free base
414202 5.0mg
EUR 288

FIPI free base
407955 200.0mg
EUR 1050

FIPI (free base)
B2372-25 each
EUR 757.2

FIPI (free base)
B2372-5 each
EUR 235.2

R406(free base)
MBS131267-100mg 100mg
EUR 1065

R406(free base)
MBS131267-500mg 500mg
EUR 2775

SIS3 (free base)
HY-100444 10 mg
EUR 1244.61
Description: SIS3 free base is a potent and selective inhibitor of Smad3 phosphorylation. SIS3 free base inhibits the myofibroblast differentiation of fibroblasts by TGF-β1. SIS3 free base does not affect the phosphorylation of Smad2[1].

R406 (free base)
HY-11108 10mM/1mL
EUR 465.38
Description: R406 free base is an orally available and competitive Syk/FLT3 inhibitor for ATP binding with a Ki of 30 nM, potently inhibits Syk kinase activity in vitro with an IC50 of 41 nM, measured at an ATP concentration corresponding to its Km value. R406 free base reduces immune complex-mediated inflammation[1]. R406 free base also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM)[2].

R406(free base)
E1KS1533 2mg
EUR 362.4

R406 free base
MBS3606124-10mg 10mg
EUR 305

R406 free base
MBS3606124-25mg 25mg
EUR 405

BIIB021 Free base