BIIB021 Free base

BIIB021 Free base

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gel casting base for evs3300
EVS3300-BASE ea
EUR 361.2

BIIB021
A4058-10 10 mg
EUR 170.4
Description: BIIB021 is a selective inhibitor of Hsp90 with Ki and EC50 values of 1.7 nM and 38 nM, respectively.[1] HSP90 (heat shock protein 90) is widely expressed as a molecular chaperone.

BIIB021
A4058-100 100 mg
EUR 505.2
Description: BIIB021 is a selective inhibitor of Hsp90 with Ki and EC50 values of 1.7 nM and 38 nM, respectively.[1] HSP90 (heat shock protein 90) is widely expressed as a molecular chaperone.

BIIB021
A4058-5 5 mg
EUR 135.6
Description: BIIB021 is a selective inhibitor of Hsp90 with Ki and EC50 values of 1.7 nM and 38 nM, respectively.[1] HSP90 (heat shock protein 90) is widely expressed as a molecular chaperone.

BIIB021
A4058-5.1 10 mM (in 1mL DMSO)
EUR 145.2
Description: BIIB021 is a selective inhibitor of Hsp90 with Ki and EC50 values of 1.7 nM and 38 nM, respectively.[1] HSP90 (heat shock protein 90) is widely expressed as a molecular chaperone.

BIIB021
A4058-50 50 mg
EUR 351.6
Description: BIIB021 is a selective inhibitor of Hsp90 with Ki and EC50 values of 1.7 nM and 38 nM, respectively.[1] HSP90 (heat shock protein 90) is widely expressed as a molecular chaperone.

BIIB021
HY-10212 50mg
EUR 408

BIIB021
27046 5 mg
EUR 130
Description: BIIB021 is an orally available, synthetic small-molecule Hsp90 inhibitor. It binds in the ATP-binding pocket of Hsp90 (Ki = 1.7 ± 0.4 nM) and induces HER-2 degradation with an EC50 of 38 ± 10 nM in MCF-7 cells. It ncreases expression of the heat shock proteins Hsp90α and Hsp70, but has no effect on expression of the nonclient protein phosphatidylinositol 3-kinase p85 subunit. BIIB021 inhibits the proliferation of N87, MCF-7, and BT474 tumor cells with IC50 values of 0.06, 0.31, and 0.14 µM, respectively. It has significant antitumor activity in N87 stomach, BT474 breast, CWR22 prostate, U87 glioblastoma, SKOV3 ovarian, and Panc-1 pancreatic tumor xenograft models.

Rucaparib (free base)
A8893-10 10 mg
EUR 240
Description: Rucaparib, also named as AG-014699 or PF-01367338, is a poly (ADP ribose) polymerase (PARP) inhibitor. PARP is a DNA damage-activated nuclear enzyme that has a key signaling role in the base excision repair pathway.

Rucaparib (free base)
A8893-200 200 mg
EUR 1243.2
Description: Rucaparib, also named as AG-014699 or PF-01367338, is a poly (ADP ribose) polymerase (PARP) inhibitor. PARP is a DNA damage-activated nuclear enzyme that has a key signaling role in the base excision repair pathway.

Rucaparib (free base)
A8893-5 5 mg
EUR 164.4
Description: Rucaparib, also named as AG-014699 or PF-01367338, is a poly (ADP ribose) polymerase (PARP) inhibitor. PARP is a DNA damage-activated nuclear enzyme that has a key signaling role in the base excision repair pathway.

Rucaparib (free base)
A8893-5.1 10 mM (in 1mL DMSO)
EUR 170.4
Description: Rucaparib, also named as AG-014699 or PF-01367338, is a poly (ADP ribose) polymerase (PARP) inhibitor. PARP is a DNA damage-activated nuclear enzyme that has a key signaling role in the base excision repair pathway.

Rucaparib (free base)
A8893-50 50 mg
EUR 547.2
Description: Rucaparib, also named as AG-014699 or PF-01367338, is a poly (ADP ribose) polymerase (PARP) inhibitor. PARP is a DNA damage-activated nuclear enzyme that has a key signaling role in the base excision repair pathway.

R406 (free base)
A5880-100 100 mg
EUR 1452
Description: R406 is a potent SYK inhibitorSpleen tyrosine kinase (SYK) is a non-receptor tyrosine kinase mainly expressed in hematopoietic cells. It transmits signals from a variety of cell surface receptors including CD74, Fc receptor and integrins.

R406 (free base)
A5880-25 25 mg
EUR 616.8
Description: R406 is a potent SYK inhibitorSpleen tyrosine kinase (SYK) is a non-receptor tyrosine kinase mainly expressed in hematopoietic cells. It transmits signals from a variety of cell surface receptors including CD74, Fc receptor and integrins.

R406 (free base)
A5880-5 5 mg
EUR 199.2
Description: R406 is a potent SYK inhibitorSpleen tyrosine kinase (SYK) is a non-receptor tyrosine kinase mainly expressed in hematopoietic cells. It transmits signals from a variety of cell surface receptors including CD74, Fc receptor and integrins.

R406 (free base)
A5880-5.1 10 mM (in 1mL DMSO)
EUR 316.8
Description: R406 is a potent SYK inhibitorSpleen tyrosine kinase (SYK) is a non-receptor tyrosine kinase mainly expressed in hematopoietic cells. It transmits signals from a variety of cell surface receptors including CD74, Fc receptor and integrins.

R406 (free base)
A5880-S Evaluation Sample
EUR 97.2
Description: R406 is a potent SYK inhibitorSpleen tyrosine kinase (SYK) is a non-receptor tyrosine kinase mainly expressed in hematopoietic cells. It transmits signals from a variety of cell surface receptors including CD74, Fc receptor and integrins.

AZD4547, Free Base
ADC-P-063 unit Ask for price

AZD8055, Free Base
ADC-P-064 unit Ask for price

Cyclopamine, Free Base
ADC-P-079 unit Ask for price

Ixabepilone, Free Base
ADC-P-104 unit Ask for price

R406(free base)
E1KS1533 2mg
EUR 625.2

Ruxolitinib (free base)
10-042 25 mg
EUR 418.2
Description: Antineoplastic, anti-inflammatory and immunomodulating agent. Orally bioavailable potent ATP mimetic that inhibits both JAK1 and JAK2 with IC50 values of 2.7 and 4.5nM, respectively and is less selective for JAK3 (IC50=322nM). Affects DC differentiation and function, leading to impaired T cell activation. Used in the treatment of myeloproliferative neoplasms and psoriasis. Anticancer agent. Shown to induce apoptosis and autophagy. Potent and selective inhibitor of HIV-1 replication and virus reactivation in vitro. It is investigated against the spread of the SARS-CoV-2 (COVID-19).

LY2835219 free base
A3575-100 100 mg
EUR 686.4
Description: LY2835219 is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity.

LY2835219 free base
A3575-25 25 mg
EUR 309.6
Description: LY2835219 is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity.

LY2835219 free base
A3575-5 5 mg
EUR 170.4
Description: LY2835219 is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity.

PLX5622 (free base)
B2965-25 25 mg
EUR 903.6

PLX5622 (free base)
B2965-5 5 mg
EUR 272.4

YM158 (free base)
HY-U00355 1mg
EUR 2770.8

Vatalanib (free base)
HY-10203 5mg
EUR 142.8

Masupirdine (free base)
HY-109118 1mg
EUR 267.6

R406 (free base)
HY-11108 10mM/1mL
EUR 277.2

ITI214 (free base)
HY-12501 100mg
EUR 3531.6

AS2863619 (free base)
HY-126675 5mg
EUR 1410

AZD3839 (free base)
HY-13438 50mg
EUR 1216.8

Ripasudil free base
HY-15685A 10mg
EUR 489.6

RPR107393 free base
HY-100299 1mg
EUR 577.2

FR167344 free base
HY-100301 1mg
EUR 3164.4

FR183998 free base
HY-100302 1mg
EUR 1352.4

FR194738 free base
HY-100303 1mg
EUR 2388

Xylazine (free base)
Q-1445.0025 25.0g
EUR 385.2
Description: Sum Formula: C12H16N2S; CAS# [7361-61-7]

TMB free base
TB0954 1g
EUR 85.06

Apatinib (Free base)
B1613-25 each
EUR 496.8

Apatinib (Free base)
B1613-5 each
EUR 170.4

Carubicin (Free base)
B1853-1 each
EUR 183.6

Carubicin (Free base)
B1853-5 each
EUR 548.4

Anlotinib, free base
B2156-25 each
EUR 705.6

Anlotinib, free base
B2156-5 each
EUR 222

FIPI (free base)
B2372-25 each
EUR 757.2

FIPI (free base)
B2372-5 each
EUR 235.2

Terbinafine (Free base)
B2423-250 each
EUR 248.4

Terbinafine (Free base)
B2423-50 each
EUR 144

THZ1 (Free base)
9664-25 each
EUR 1227.6

THZ1 (Free base)
9664-5 each
EUR 352.8

MCC950 (Free base)
B1031-1 each
EUR 183.6

MCC950 (Free base)
B1031-5 each
EUR 548.4

Vatalanib, Free Base
2026-25 each
EUR 366

Vatalanib, Free Base
2026-5 each
EUR 151.2

Erlotinib, Free Base
2048-100 each
EUR 189.6

Erlotinib, Free Base
2048-1000 each
EUR 464.4

Sunitinib, Free base
2097-100 each
EUR 229.2

Sunitinib, Free base
2097-1000 each
EUR 601.2

Sunitinib, Free base
2097-25 each
EUR 138

Lapatinib, Free base
2138-100 each
EUR 464.4

Lapatinib, Free base
2138-25 each
EUR 229.2

Ruxolitinib, Free base
2139-100 each Ask for price

Ruxolitinib, Free base
2139-25 each
EUR 639.6

Ruxolitinib, Free base
2139-5 each
EUR 248.4

Imatinib, Free base
2141-100 each
EUR 176.4

Imatinib, Free base
2141-1000 each
EUR 502.8

Linsitinib, Free base
2294-25 each
EUR 679.2

Linsitinib, Free base
2294-5 each
EUR 222

Tipifarnib, Free base
2296-1 each
EUR 170.4

Tipifarnib, Free base
2296-5 each
EUR 496.8

Cyclopamine, Free Base
27013 10 mg
EUR 130
Description: Cyclopamine inhibits activation of the Hedgehog response pathway by binding to and inhibiting the proto-oncogene Smoothened (SMO). The effects of oncogenic mutations that either activate SMO or inactivate the tumor suppressor Patched (Ptch) can be reversed by cyclopamine treatment. Cyclopamine has also been shown to induce apoptosis in colorectal adenoma cell lines, carcinoma-derived cell lines, and skin basal cell carcinomas and is being investigated as an anti-cancer drug.

SGI-1776 free base
A4192-10 10 mg
EUR 296.4
Description: SGI-1776 free base, N-((1-methylpiperidin-4-yl)methyl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazin-6-amine, is a potent ATP-competitive inhibitor of the serine/threonine family of Pim kinase, an enzyme regulating cell survival.

SGI-1776 free base
A4192-5 5 mg
EUR 184.8
Description: SGI-1776 free base, N-((1-methylpiperidin-4-yl)methyl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazin-6-amine, is a potent ATP-competitive inhibitor of the serine/threonine family of Pim kinase, an enzyme regulating cell survival.

SGI-1776 free base
A4192-5.1 10 mM (in 1mL DMSO)
EUR 199.2
Description: SGI-1776 free base, N-((1-methylpiperidin-4-yl)methyl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazin-6-amine, is a potent ATP-competitive inhibitor of the serine/threonine family of Pim kinase, an enzyme regulating cell survival.

SGI-1776 free base
A4192-50 50 mg
EUR 630
Description: SGI-1776 free base, N-((1-methylpiperidin-4-yl)methyl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazin-6-amine, is a potent ATP-competitive inhibitor of the serine/threonine family of Pim kinase, an enzyme regulating cell survival.

SGI-1776 free base
A4192-S Evaluation Sample
EUR 97.2
Description: SGI-1776 free base, N-((1-methylpiperidin-4-yl)methyl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazin-6-amine, is a potent ATP-competitive inhibitor of the serine/threonine family of Pim kinase, an enzyme regulating cell survival.

AM-095 free base
A3167-10 10 mg
EUR 254.4
Description: AM095 is a novel, potent and orally bioavailable antagonist of lysophosphatidic acid type 1 receptor (LPA1) with IC50 values of 0.73 and 0.98 ?M for mouse or recombinant human LPA1, respectively [1].

AM-095 free base
A3167-100 100 mg
EUR 964.8
Description: AM095 is a novel, potent and orally bioavailable antagonist of lysophosphatidic acid type 1 receptor (LPA1) with IC50 values of 0.73 and 0.98 ?M for mouse or recombinant human LPA1, respectively [1].

AM-095 free base
A3167-200 200 mg
EUR 1382.4
Description: AM095 is a novel, potent and orally bioavailable antagonist of lysophosphatidic acid type 1 receptor (LPA1) with IC50 values of 0.73 and 0.98 ?M for mouse or recombinant human LPA1, respectively [1].

AM-095 free base
A3167-5 5 mg
EUR 199.2
Description: AM095 is a novel, potent and orally bioavailable antagonist of lysophosphatidic acid type 1 receptor (LPA1) with IC50 values of 0.73 and 0.98 ?M for mouse or recombinant human LPA1, respectively [1].

AM-095 free base
A3167-50 50 mg
EUR 686.4
Description: AM095 is a novel, potent and orally bioavailable antagonist of lysophosphatidic acid type 1 receptor (LPA1) with IC50 values of 0.73 and 0.98 ?M for mouse or recombinant human LPA1, respectively [1].

L-Arginine free base
AB0205 100g
EUR 75.78

Staurosporine, >99% Free Base
BC090-001 1mg
EUR 295.2

Staurosporine, >99% Free Base
BC090-005 5mg
EUR 408

Vandetanib, >99% Free Base
BC098-025 25mg
EUR 278.4

Vandetanib, >99% Free Base
BC098-050 50mg
EUR 343.2

Vandetanib, >99% Free Base
BC098-100 100mg
EUR 375.6

Vandetanib, >100% Free Base
BC098-500 500mg
EUR 789.6

SB-334867 free base
B3423-100 100 mg
EUR 718.8
Description: SB-334867 free base is a selective antagonist of orexin-1 receptor [1].Orexin-A and orexin-B are two peptides isolated from rat hypothalamus. They are involved in some physiological functions such as the control of feeding, energy metabolism and regulation of the sleep-wake cycle.

SB-334867 free base
B3423-25 25 mg
EUR 348
Description: SB-334867 free base is a selective antagonist of orexin-1 receptor [1].Orexin-A and orexin-B are two peptides isolated from rat hypothalamus. They are involved in some physiological functions such as the control of feeding, energy metabolism and regulation of the sleep-wake cycle.

SB-334867 free base
B3423-5 5 mg
EUR 153.6
Description: SB-334867 free base is a selective antagonist of orexin-1 receptor [1].Orexin-A and orexin-B are two peptides isolated from rat hypothalamus. They are involved in some physiological functions such as the control of feeding, energy metabolism and regulation of the sleep-wake cycle.

SB-334867 free base
B3423-5.1 10 mM (in 1mL DMSO)
EUR 157.2
Description: SB-334867 free base is a selective antagonist of orexin-1 receptor [1].Orexin-A and orexin-B are two peptides isolated from rat hypothalamus. They are involved in some physiological functions such as the control of feeding, energy metabolism and regulation of the sleep-wake cycle.

BMS-345541(free base)
B4655-10 10 mg
EUR 282
Description: BMS-345541(free base) is a selective inhibitor of IKK-1 and IKK-2 with IC50 value of 4?M and 0.3?M, respectively [1].IKK is also known as nuclear factor kappa-B kinase subunit inhibitor and involves in cytokine-activated intracellular signaling pathways.

BMS-345541(free base)
B4655-5 5 mg
EUR 205.2
Description: BMS-345541(free base) is a selective inhibitor of IKK-1 and IKK-2 with IC50 value of 4?M and 0.3?M, respectively [1].IKK is also known as nuclear factor kappa-B kinase subunit inhibitor and involves in cytokine-activated intracellular signaling pathways.

BMS-345541(free base)
B4655-50 50 mg
EUR 714
Description: BMS-345541(free base) is a selective inhibitor of IKK-1 and IKK-2 with IC50 value of 4?M and 0.3?M, respectively [1].IKK is also known as nuclear factor kappa-B kinase subunit inhibitor and involves in cytokine-activated intracellular signaling pathways.

GSK J4 free base
B5959-10 10 mg
EUR 447.6
Description: GSK J4 free base

GSK J4 free base
B5959-50 50 mg
EUR 1437.6
Description: GSK J4 free base

CP-319340(free base)
HY-U00270 5mg
EUR 1052.4

AV-412 (free base)
HY-10346A 5mg
EUR 207.6

SB-334867 (free base)
HY-10895A 10mg
EUR 258

SNT-207858 (free base)
HY-11030A 10mg
EUR 1093.2

APX-115 (free base)
HY-120801A 5mg
EUR 267.6

LY-2584702 (free base)
HY-12493 5mg
EUR 198

Genz-123346 (free base)
HY-12744 10mM/1mL
EUR 226.8

YHO-13351 (free base)
HY-12758A 10mM/1mL
EUR 211.2

JTV-519 (free base)
HY-15293A 5mg
EUR 680.4

RGB-286638 (free base)
HY-15504A 100mg
EUR 3364.8

DOV-216,303 (Free Base)
HY-18332C 10mM/1mL
EUR 590.4

FK-448 Free base
HY-100193 10mg
EUR 2264.4

KW-8232 free base
HY-100304 10mg
EUR 6021.6

YM-53601 free base
HY-100313 1mg
EUR 1870.8

Z-NHNH2 (free base)
Q-1150.0025 25.0g
EUR 151.2
Description: Sum Formula: C8H10N2O2; CAS# [5331-43-1]

Z-NHNH2 (free base)
Q-1150.0100 100.0g
EUR 385.2
Description: Sum Formula: C8H10N2O2; CAS# [5331-43-1]

BMS-345541 (Free base)
B1907-1 each
EUR 170.4

BMS-345541 (Free base)
B1907-5 each
EUR 496.8

UNC-926, free base
B2158-25 each
EUR 757.2

UNC-926, free base
B2158-5 each
EUR 235.2

BIIB021 Free base