LKB1/MO25/STRAD Complex
Contact us: [email protected]
STRAD antibody |
70R-31975 |
Fitzgerald |
100 ug |
EUR 392.4 |
Description: Rabbit polyclonal STRAD antibody |
STRAD Antibody |
33947-100ul |
SAB |
100ul |
EUR 302.4 |
STRAD Antibody |
33947-50ul |
SAB |
50ul |
EUR 224.4 |
STRAD Antibody |
8C11258 |
AAT Bioquest |
50ug |
EUR 368 |
Description: STRAD Antibody |
STRAD Antibody |
E11-11258C |
EnoGene |
100μg |
EUR 225 |
Description: Available in various conjugation types. |
STRAD Antibody |
E033947 |
EnoGene |
100μg/100μl |
EUR 255 |
Description: Available in various conjugation types. |
STRAD Antibody |
E18-0572-1 |
EnoGene |
50μg/50μl |
EUR 145 |
Description: Available in various conjugation types. |
STRAD Antibody |
E18-0572-2 |
EnoGene |
100μg/100μl |
EUR 225 |
Description: Available in various conjugation types. |
STRAD Antibody |
E19-3334 |
EnoGene |
100μg/100μl |
EUR 225 |
Description: Available in various conjugation types. |
STRAD Antibody |
33947 |
SAB |
100ul |
EUR 319 |
LKB1 |
E8ER1912-41 |
EnoGene |
100ul |
EUR 275 |
Description: Available in various conjugation types. |
Monoclonal Mo25 Antibody, Clone: EP1680Y |
APR07134G |
Leading Biology |
0.1ml |
EUR 633.6 |
Description: A Monoclonal antibody against Human Mo25. The antibodies are raised in Rabbit and are from clone EP1680Y. This antibody is applicable in WB and IHC |
STRAD Blocking Peptide |
AF0572-BP |
Affbiotech |
1mg |
EUR 234 |
STRAD Blocking Peptide |
DF3334-BP |
Affbiotech |
1mg |
EUR 234 |
STRAD Conjugated Antibody |
C33947 |
SAB |
100ul |
EUR 476.4 |
Strad Polyclonal Antibody |
ABP52525-003ml |
Abbkine |
0.03ml |
EUR 189.6 |
|
Description: A polyclonal antibody for detection of Strad from Human, Mouse. This Strad antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human Strad at AA range: 30-110 |
Strad Polyclonal Antibody |
ABP52525-01ml |
Abbkine |
0.1ml |
EUR 346.8 |
|
Description: A polyclonal antibody for detection of Strad from Human, Mouse. This Strad antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human Strad at AA range: 30-110 |
Strad Polyclonal Antibody |
ABP52525-02ml |
Abbkine |
0.2ml |
EUR 496.8 |
|
Description: A polyclonal antibody for detection of Strad from Human, Mouse. This Strad antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human Strad at AA range: 30-110 |
Strad Polyclonal Antibody |
ES3524-100ul |
ELK Biotech |
100ul |
EUR 334.8 |
Description: A Rabbit Polyclonal antibody against Strad from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
Strad Polyclonal Antibody |
ES3524-50ul |
ELK Biotech |
50ul |
EUR 248.4 |
Description: A Rabbit Polyclonal antibody against Strad from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
Strad Polyclonal Antibody |
E20-74464 |
EnoGene |
100ug |
EUR 225 |
Description: Available in various conjugation types. |
LKB1 Peptide |
3987P |
ProSci |
0.05 mg |
EUR 197.7 |
Description: (CT) LKB1 peptide |
LKB1 Antibody |
24473-100ul |
SAB |
100ul |
EUR 468 |
LKB1 Antibody |
3950-100 |
Biovision |
each |
EUR 379.2 |
LKB1 Antibody |
3950-30T |
Biovision |
each |
EUR 175.2 |
LKB1 Antibody |
3987-002mg |
ProSci |
0.02 mg |
EUR 206.18 |
|
Description: LKB1 Antibody: The LKB1 serine/threonine protein kinase was initially identified as a tumor suppressor gene mutated in human Peutz-Jeghers syndrome (PJS), a condition resulting in the growth of numerous intestinal polyps classed as hamartomas. LKB1 exists as a heterotrimeric complex with two other proteins, Ste20-related adaptor protein (STRAD) and MO25. Together, this complex can phsophorylate and activate the AMP-activate protein kinase (AMPK). Following AMPK activation by LKB1, AMPK then phosphorylates TSC1 and TSC2, key components of the metabolism-regulating TOR signaling pathway, which antagonizes the activation for the TOR pathway. LKB1 has also been shown to play a fundamental role in controlling the spatial orientation of structures required to maintain an ordered, polarized epithelium. |
LKB1 Antibody |
3987-01mg |
ProSci |
0.1 mg |
EUR 523.7 |
|
Description: LKB1 Antibody: The LKB1 serine/threonine protein kinase was initially identified as a tumor suppressor gene mutated in human Peutz-Jeghers syndrome (PJS), a condition resulting in the growth of numerous intestinal polyps classed as hamartomas. LKB1 exists as a heterotrimeric complex with two other proteins, Ste20-related adaptor protein (STRAD) and MO25. Together, this complex can phsophorylate and activate the AMP-activate protein kinase (AMPK). Following AMPK activation by LKB1, AMPK then phosphorylates TSC1 and TSC2, key components of the metabolism-regulating TOR signaling pathway, which antagonizes the activation for the TOR pathway. LKB1 has also been shown to play a fundamental role in controlling the spatial orientation of structures required to maintain an ordered, polarized epithelium. |
LKB1 antibody |
70R-12216 |
Fitzgerald |
100 ug |
EUR 483.6 |
Description: Rabbit polyclonal LKB1 antibody |
LKB1 antibody |
70R-32666 |
Fitzgerald |
100 ug |
EUR 392.4 |
Description: Rabbit polyclonal LKB1 antibody |
LKB1 antibody |
70R-51648 |
Fitzgerald |
100 ul |
EUR 292.8 |
Description: Purified Polyclonal LKB1 antibody |
LKB1 antibody |
70R-51649 |
Fitzgerald |
100 ul |
EUR 292.8 |
Description: Purified Polyclonal LKB1 antibody |
LKB1 antibody |
70R-50441 |
Fitzgerald |
100 ul |
EUR 344.4 |
Description: Purified Polyclonal LKB1 antibody |
LKB1 antibody |
70R-35092 |
Fitzgerald |
100 ug |
EUR 392.4 |
Description: Purified Rabbit polyclonal LKB1 antibody |
LKB1 antibody |
70R-35972 |
Fitzgerald |
100 ug |
EUR 392.4 |
Description: Rabbit polyclonal LKB1 antibody |
LKB1 Antibody |
F50221-0.4ML |
NSJ Bioreagents |
0.4 ml |
EUR 322.15 |
Description: LKB1 is a tumor suppressor serine/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. Acts by phosphorylating the T-loop of AMPK family proteins, thus promoting their activity: phosphorylates PRKAA1, PRKAA2, BRSK1, BRSK2, MARK1, MARK2, MARK3, MARK4, NUAK1, NUAK2, SIK1, SIK2, SIK3 and SNRK but not MELK. Also phosphorylates non-AMPK family proteins such as STRADA, PTEN and possibly p53/TP53. Acts as a key upstream regulator of AMPK by mediating phosphorylation and activation of AMPK catalytic subunits PRKAA1 and PRKAA2 and thereby regulates processes including: inhibition of signaling pathways that promote cell growth and proliferation when energy levels are low, glucose homeostasis in liver, activation of autophagy when cells undergo nutrient deprivation, and B-cell differentiation in the germinal center in response to DNA damage. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton. Required for cortical neuron polarization by mediating phosphorylation and activation of BRSK1 and BRSK2, leading to axon initiation and specification. Involved in DNA damage response: interacts with p53/TP53 and recruited to the CDKN1A/WAF1 promoter to participate in transcription activation. Able to phosphorylate p53/TP53; the relevance of such result in vivo is however unclear and phosphorylation may be indirect and mediated by downstream STK11/LKB1 kinase NUAK1. Also acts as a mediator of p53/TP53-dependent apoptosis via interaction with p53/TP53: translocates to the mitochondrion during apoptosis and regulates p53/TP53-dependent apoptosis pathways. In vein endothelial cells, inhibits PI3K/Akt signaling activity and thus induces apoptosis in response to the oxidant peroxynitrite (in vitro). Regulates UV radiation-induced DNA damage response mediated by CDKN1A. In association with NUAK1, phosphorylates CDKN1A in response to UV radiation and contributes to its degradation which is necessary for optimal DNA repair. [UniProt] |
LKB1 Antibody |
F50223-0.4ML |
NSJ Bioreagents |
0.4 ml |
EUR 322.15 |
Description: LKB1 is a tumor suppressor serine/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. Acts as a key upstream regulator of AMPK by mediating phosphorylation and activation of AMPK catalytic subunits PRKAA1 and PRKAA2 and thereby regulates processes including: inhibition of signaling pathways that promote cell growth and proliferation when energy levels are low, glucose homeostasis in liver, activation of autophagy when cells undergo nutrient deprivation, and B-cell differentiation in the germinal center in response to DNA damage. [UniProt] |
LKB1 Antibody |
R31683 |
NSJ Bioreagents |
100 ug |
EUR 356.15 |
Description: Serine/threonine kinase 11 or LKB1 is a protein kinase which in humans is encoded by the STK11 gene. The STK11 gene, which encodes a member of the serine/threonine kinase, regulates cell polarity and functions as a tumour suppressor. STK11 is a primary upstream kinase of adenine monophosphate-activated protein kinase (AMPK), a necessary element in cell metabolism that is required for maintaining energy homeostasis. It has been found that LKB1 physically associates with p53 and regulates specific p53-dependent apoptosis pathways. |
LKB1 Antibody |
E38PA3330 |
EnoGene |
100ul |
EUR 225 |
Description: Available in various conjugation types. |
LKB1 Antibody |
E18-6453-1 |
EnoGene |
50μg/50μl |
EUR 145 |
Description: Available in various conjugation types. |
LKB1 Antibody |
E18-6453-2 |
EnoGene |
100μg/100μl |
EUR 225 |
Description: Available in various conjugation types. |
LKB1 Antibody |
E18-6454-1 |
EnoGene |
50μg/50μl |
EUR 145 |
Description: Available in various conjugation types. |
LKB1 Antibody |
E18-6454-2 |
EnoGene |
100μg/100μl |
EUR 225 |
Description: Available in various conjugation types. |
LKB1 Antibody |
24473 |
SAB |
100ul |
EUR 479 |
LKB1 Rabbit pAb |
A2122-100ul |
Abclonal |
100 ul |
EUR 369.6 |
LKB1 Rabbit pAb |
A2122-200ul |
Abclonal |
200 ul |
EUR 550.8 |
LKB1 Rabbit pAb |
A2122-20ul |
Abclonal |
20 ul |
EUR 219.6 |
LKB1 Rabbit pAb |
A2122-50ul |
Abclonal |
50 ul |
EUR 267.6 |
LKB1 Rabbit pAb |
E2344678 |
EnoGene |
100μl |
EUR 225 |
Description: Available in various conjugation types. |
anti- LKB1 antibody |
FNab04802 |
FN Test |
100µg |
EUR 658.5 |
|
Description: Antibody raised against LKB1 |
LKB1 (pS334) Antibody |
abx218798-100ug |
Abbexa |
100 ug |
EUR 526.8 |
|
LKB1 (pT189) Antibody |
20-abx133342 |
Abbexa |
-
EUR 376.80
-
EUR 560.40
-
EUR 243.60
|
|
|
LKB1 (pS428) Antibody |
20-abx009818 |
Abbexa |
-
EUR 376.80
-
EUR 560.40
-
EUR 243.60
|
|
|
LKB1 (pT189) Antibody |
abx012324-100ug |
Abbexa |
100 ug |
EUR 526.8 |
|
LKB1 (pS428) Antibody |
abx012326-100ug |
Abbexa |
100 ug |
EUR 526.8 |
|
STK11 Antibody (LKB1) |
F50222-0.4ML |
NSJ Bioreagents |
0.4 ml |
EUR 322.15 |
Description: STK11, is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. |
LKB1 (pT189) Antibody |
E38PA4840 |
EnoGene |
100ul |
EUR 225 |
Description: Available in various conjugation types. |
LKB1 antibody (Ser334) |
70R-32665 |
Fitzgerald |
100 ug |
EUR 392.4 |
Description: Rabbit polyclonal LKB1 antibody (Ser334) |
LKB1/MO25/STRAD Complex