LKB1/MO25/STRAD Complex

LKB1/MO25/STRAD Complex

Contact us: [email protected]

STRAD antibody

70R-31975 100 ug
EUR 392.4
Description: Rabbit polyclonal STRAD antibody

STRAD Antibody

33947-100ul 100ul
EUR 302.4

STRAD Antibody

33947-50ul 50ul
EUR 224.4

STRAD Antibody

ABD3334 100 ug
EUR 525.6

STRAD Antibody

ABF0572 100 ug
EUR 525.6

STRAD Antibody

DF3334 100ul
EUR 280
Description: Human,Mouse

STRAD Antibody

AF0572 100ul
EUR 280
Description: Human,Mouse,Rat

STRAD Antibody

8C11258 50ug
EUR 368
Description: STRAD Antibody

STRAD Antibody

E11-11258C 100μg
EUR 225
Description: Available in various conjugation types.

STRAD Antibody

E033947 100μg/100μl
EUR 255
Description: Available in various conjugation types.

STRAD Antibody

AF0572-100ul 100ul
EUR 280

STRAD Antibody

AF0572-200ul 200ul
EUR 350

STRAD Antibody

E18-0572-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

STRAD Antibody

E18-0572-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

STRAD Antibody

E19-3334 100μg/100μl
EUR 225
Description: Available in various conjugation types.

STRAD Antibody

DF3334-100ul 100ul
EUR 280

STRAD Antibody

DF3334-200ul 200ul
EUR 350

STRAD Antibody

33947 100ul
EUR 319

LKB1

E8ER1912-41 100ul
EUR 275
Description: Available in various conjugation types.

Monoclonal Mo25 Antibody, Clone: EP1680Y

APR07134G 0.1ml
EUR 633.6
Description: A Monoclonal antibody against Human Mo25. The antibodies are raised in Rabbit and are from clone EP1680Y. This antibody is applicable in WB and IHC

STRAD Blocking Peptide

AF0572-BP 1mg
EUR 234

STRAD Blocking Peptide

DF3334-BP 1mg
EUR 234

STRAD Conjugated Antibody

C33947 100ul
EUR 476.4

Strad Polyclonal Antibody

ABP52525-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Strad from Human, Mouse. This Strad antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human Strad at AA range: 30-110

Strad Polyclonal Antibody

ABP52525-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Strad from Human, Mouse. This Strad antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human Strad at AA range: 30-110

Strad Polyclonal Antibody

ABP52525-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Strad from Human, Mouse. This Strad antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human Strad at AA range: 30-110

Strad Polyclonal Antibody

ES3524-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against Strad from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

Strad Polyclonal Antibody

ES3524-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against Strad from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

Strad Polyclonal Antibody

E20-74464 100ug
EUR 225
Description: Available in various conjugation types.

LKB1 Peptide

3987P 0.05 mg
EUR 197.7
Description: (CT) LKB1 peptide

LKB1 Antibody

24473-100ul 100ul
EUR 468

LKB1 Antibody

3950-100 each
EUR 379.2

LKB1 Antibody

3950-30T each
EUR 175.2

LKB1 Antibody

3987-002mg 0.02 mg
EUR 206.18
Description: LKB1 Antibody: The LKB1 serine/threonine protein kinase was initially identified as a tumor suppressor gene mutated in human Peutz-Jeghers syndrome (PJS), a condition resulting in the growth of numerous intestinal polyps classed as hamartomas. LKB1 exists as a heterotrimeric complex with two other proteins, Ste20-related adaptor protein (STRAD) and MO25. Together, this complex can phsophorylate and activate the AMP-activate protein kinase (AMPK). Following AMPK activation by LKB1, AMPK then phosphorylates TSC1 and TSC2, key components of the metabolism-regulating TOR signaling pathway, which antagonizes the activation for the TOR pathway. LKB1 has also been shown to play a fundamental role in controlling the spatial orientation of structures required to maintain an ordered, polarized epithelium.

LKB1 Antibody

3987-01mg 0.1 mg
EUR 523.7
Description: LKB1 Antibody: The LKB1 serine/threonine protein kinase was initially identified as a tumor suppressor gene mutated in human Peutz-Jeghers syndrome (PJS), a condition resulting in the growth of numerous intestinal polyps classed as hamartomas. LKB1 exists as a heterotrimeric complex with two other proteins, Ste20-related adaptor protein (STRAD) and MO25. Together, this complex can phsophorylate and activate the AMP-activate protein kinase (AMPK). Following AMPK activation by LKB1, AMPK then phosphorylates TSC1 and TSC2, key components of the metabolism-regulating TOR signaling pathway, which antagonizes the activation for the TOR pathway. LKB1 has also been shown to play a fundamental role in controlling the spatial orientation of structures required to maintain an ordered, polarized epithelium.

LKB1 antibody

70R-12216 100 ug
EUR 483.6
Description: Rabbit polyclonal LKB1 antibody

LKB1 antibody

70R-32666 100 ug
EUR 392.4
Description: Rabbit polyclonal LKB1 antibody

LKB1 antibody

70R-51648 100 ul
EUR 292.8
Description: Purified Polyclonal LKB1 antibody

LKB1 antibody

70R-51649 100 ul
EUR 292.8
Description: Purified Polyclonal LKB1 antibody

LKB1 antibody

70R-50441 100 ul
EUR 344.4
Description: Purified Polyclonal LKB1 antibody

LKB1 antibody

70R-35092 100 ug
EUR 392.4
Description: Purified Rabbit polyclonal LKB1 antibody

LKB1 antibody

70R-35972 100 ug
EUR 392.4
Description: Rabbit polyclonal LKB1 antibody

LKB1 Antibody

ABF6453 100 ug
EUR 525.6

LKB1 Antibody

ABF6454 100 ug
EUR 525.6

LKB1 Antibody

F50221-0.4ML 0.4 ml
EUR 322.15
Description: LKB1 is a tumor suppressor serine/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. Acts by phosphorylating the T-loop of AMPK family proteins, thus promoting their activity: phosphorylates PRKAA1, PRKAA2, BRSK1, BRSK2, MARK1, MARK2, MARK3, MARK4, NUAK1, NUAK2, SIK1, SIK2, SIK3 and SNRK but not MELK. Also phosphorylates non-AMPK family proteins such as STRADA, PTEN and possibly p53/TP53. Acts as a key upstream regulator of AMPK by mediating phosphorylation and activation of AMPK catalytic subunits PRKAA1 and PRKAA2 and thereby regulates processes including: inhibition of signaling pathways that promote cell growth and proliferation when energy levels are low, glucose homeostasis in liver, activation of autophagy when cells undergo nutrient deprivation, and B-cell differentiation in the germinal center in response to DNA damage. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton. Required for cortical neuron polarization by mediating phosphorylation and activation of BRSK1 and BRSK2, leading to axon initiation and specification. Involved in DNA damage response: interacts with p53/TP53 and recruited to the CDKN1A/WAF1 promoter to participate in transcription activation. Able to phosphorylate p53/TP53; the relevance of such result in vivo is however unclear and phosphorylation may be indirect and mediated by downstream STK11/LKB1 kinase NUAK1. Also acts as a mediator of p53/TP53-dependent apoptosis via interaction with p53/TP53: translocates to the mitochondrion during apoptosis and regulates p53/TP53-dependent apoptosis pathways. In vein endothelial cells, inhibits PI3K/Akt signaling activity and thus induces apoptosis in response to the oxidant peroxynitrite (in vitro). Regulates UV radiation-induced DNA damage response mediated by CDKN1A. In association with NUAK1, phosphorylates CDKN1A in response to UV radiation and contributes to its degradation which is necessary for optimal DNA repair. [UniProt]

LKB1 Antibody

F50223-0.4ML 0.4 ml
EUR 322.15
Description: LKB1 is a tumor suppressor serine/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. Acts as a key upstream regulator of AMPK by mediating phosphorylation and activation of AMPK catalytic subunits PRKAA1 and PRKAA2 and thereby regulates processes including: inhibition of signaling pathways that promote cell growth and proliferation when energy levels are low, glucose homeostasis in liver, activation of autophagy when cells undergo nutrient deprivation, and B-cell differentiation in the germinal center in response to DNA damage. [UniProt]

LKB1 Antibody

AF7898 100ul
EUR 350
Description: Human,Mouse

LKB1 Antibody

AF6453 100ul
EUR 280
Description: Human,Mouse,Monkey

LKB1 Antibody

AF6454 100ul
EUR 280
Description: Human,Mouse,Rat

LKB1 Antibody

DF6846 100ul
EUR 280
Description: Human,Mouse,Rat

LKB1 Antibody

R31683 100 ug
EUR 356.15
Description: Serine/threonine kinase 11 or LKB1 is a protein kinase which in humans is encoded by the STK11 gene. The STK11 gene, which encodes a member of the serine/threonine kinase, regulates cell polarity and functions as a tumour suppressor. STK11 is a primary upstream kinase of adenine monophosphate-activated protein kinase (AMPK), a necessary element in cell metabolism that is required for maintaining energy homeostasis. It has been found that LKB1 physically associates with p53 and regulates specific p53-dependent apoptosis pathways.

LKB1 antibody

CAF50203-100ug 100ug
EUR 338

LKB1 Antibody

E38PA3330 100ul
EUR 225
Description: Available in various conjugation types.

LKB1 Antibody

AF6453-100ul 100ul
EUR 280

LKB1 Antibody

AF6453-200ul 200ul
EUR 350

LKB1 Antibody

AF6454-100ul 100ul
EUR 280

LKB1 Antibody

AF6454-200ul 200ul
EUR 350

LKB1 Antibody

AF7898-100ul 100ul
EUR 350

LKB1 Antibody

AF7898-200ul 200ul
EUR 450

LKB1 Antibody

AF7898-50ul 50ul
EUR 250

LKB1 Antibody

E18-6453-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

LKB1 Antibody

E18-6453-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

LKB1 Antibody

E18-6454-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

LKB1 Antibody

E18-6454-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

LKB1 Antibody

DF6846-100ul 100ul
EUR 280

LKB1 Antibody

DF6846-200ul 200ul
EUR 350

LKB1 Antibody

24473 100ul
EUR 479

LKB1 Rabbit pAb

A2122-100ul 100 ul
EUR 369.6

LKB1 Rabbit pAb

A2122-200ul 200 ul
EUR 550.8

LKB1 Rabbit pAb

A2122-20ul 20 ul
EUR 219.6

LKB1 Rabbit pAb

A2122-50ul 50 ul
EUR 267.6

LKB1 Rabbit pAb

E2344678 100μl
EUR 225
Description: Available in various conjugation types.

anti- LKB1 antibody

FNab04802 100µg
EUR 658.5
Description: Antibody raised against LKB1

LKB1 (pS334) Antibody

abx218798-100ug 100 ug
EUR 526.8

LKB1 (pT189) Antibody

20-abx133342
  • EUR 376.80
  • EUR 560.40
  • EUR 243.60
  • 100 ul
  • 200 ul
  • 30 ul

LKB1 (pS428) Antibody

20-abx009818
  • EUR 376.80
  • EUR 560.40
  • EUR 243.60
  • 100 ul
  • 200 ul
  • 30 ul

LKB1 (pT189) Antibody

abx012324-100ug 100 ug
EUR 526.8

LKB1 (pS428) Antibody

abx012326-100ug 100 ug
EUR 526.8

STK11 Antibody (LKB1)

F50222-0.4ML 0.4 ml
EUR 322.15
Description: STK11, is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.

LKB1 (pT189) Antibody

E38PA4840 100ul
EUR 225
Description: Available in various conjugation types.

LKB1 antibody (Ser334)

70R-32665 100 ug
EUR 392.4
Description: Rabbit polyclonal LKB1 antibody (Ser334)

LKB1/MO25/STRAD Complex